Motamedi-Shad N - Search Results

1

A single-chain variable fragment intrabody prevents intracellular polymerization of Z α1-antitrypsin while allowing its antiproteinase activity.

Ordóñez A, Pérez J, Tan L, Dickens JA, Motamedi-Shad N, Irving JA, Haq I, Ekeowa U, Marciniak SJ, Miranda E, Lomas DA. Ordóñez A, et al. Among authors: motamedi shad n. FASEB J. 2015 Jun;29(6):2667-78. doi: 10.1096/fj.14-267351. Epub 2015 Mar 10. FASEB J. 2015. PMID: 25757566 Free PMC article.

2

An antibody raised against a pathogenic serpin variant induces mutant-like behaviour in the wild-type protein.

Irving JA, Miranda E, Haq I, Perez J, Kotov VR, Faull SV, Motamedi-Shad N, Lomas DA. Irving JA, et al. Among authors: motamedi shad n. Biochem J. 2015 May 15;468(1):99-108. doi: 10.1042/BJ20141569. Biochem J. 2015. PMID: 25738741 Free PMC article.

3

Deficiency Mutations of Alpha-1 Antitrypsin. Effects on Folding, Function, and Polymerization.

Haq I, Irving JA, Saleh AD, Dron L, Regan-Mochrie GL, Motamedi-Shad N, Hurst JR, Gooptu B, Lomas DA. Haq I, et al. Among authors: motamedi shad n. Am J Respir Cell Mol Biol. 2016 Jan;54(1):71-80. doi: 10.1165/rcmb.2015-0154OC. Am J Respir Cell Mol Biol. 2016. PMID: 26091018 Free PMC article.

4

An antibody that prevents serpin polymerisation acts by inducing a novel allosteric behaviour.

Motamedi-Shad N, Jagger AM, Liedtke M, Faull SV, Nanda AS, Salvadori E, Wort JL, Kay CW, Heyer-Chauhan N, Miranda E, Perez J, Ordóñez A, Haq I, Irving JA, Lomas DA. Motamedi-Shad N, et al. Biochem J. 2016 Oct 1;473(19):3269-90. doi: 10.1042/BCJ20160159. Epub 2016 Jul 12. Biochem J. 2016. PMID: 27407165 Free PMC article.

5

Rapid oligomer formation of human muscle acylphosphatase induced by heparan sulfate.

Motamedi-Shad N, Garfagnini T, Penco A, Relini A, Fogolari F, Corazza A, Esposito G, Bemporad F, Chiti F. Motamedi-Shad N, et al. Nat Struct Mol Biol. 2012 Apr 22;19(5):547-54, S1-2. doi: 10.1038/nsmb.2286. Nat Struct Mol Biol. 2012. PMID: 22522822

6

Amyloid formation by the model protein muscle acylphosphatase is accelerated by heparin and heparan sulphate through a scaffolding-based mechanism.

Motamedi-Shad N, Monsellier E, Chiti F. Motamedi-Shad N, et al. J Biochem. 2009 Dec;146(6):805-14. doi: 10.1093/jb/mvp128. Epub 2009 Aug 12. J Biochem. 2009. PMID: 19675100

7

Kinetic analysis of amyloid formation in the presence of heparan sulfate: faster unfolding and change of pathway.

Motamedi-Shad N, Monsellier E, Torrassa S, Relini A, Chiti F. Motamedi-Shad N, et al. J Biol Chem. 2009 Oct 23;284(43):29921-34. doi: 10.1074/jbc.M109.018747. Epub 2009 Aug 21. J Biol Chem. 2009. PMID: 19700762 Free PMC article.

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