Lakshmana MK - Search Results

1

A comparative evaluation of a novel vaccine in APP/PS1 mouse models of Alzheimer's disease.

Carrera I, Etcheverría I, Fernández-Novoa L, Lombardi VR, Lakshmana MK, Cacabelos R, Vigo C. Carrera I, et al. Among authors: lakshmana mk. Biomed Res Int. 2015;2015:807146. doi: 10.1155/2015/807146. Epub 2015 Feb 11. Biomed Res Int. 2015. PMID: 25759822 Free PMC article.

2

COPS5 protein overexpression increases amyloid plaque burden, decreases spinophilin-immunoreactive puncta, and exacerbates learning and memory deficits in the mouse brain.

Wang R, Wang H, Carrera I, Xu S, Lakshmana MK. Wang R, et al. Among authors: lakshmana mk. J Biol Chem. 2015 Apr 3;290(14):9299-309. doi: 10.1074/jbc.M114.595926. Epub 2015 Feb 20. J Biol Chem. 2015. PMID: 25713139 Free PMC article.

3

COPS5 (Jab1) protein increases β site processing of amyloid precursor protein and amyloid β peptide generation by stabilizing RanBP9 protein levels.

Wang H, Dey D, Carrera I, Minond D, Bianchi E, Xu S, Lakshmana MK. Wang H, et al. Among authors: lakshmana mk. J Biol Chem. 2013 Sep 13;288(37):26668-77. doi: 10.1074/jbc.M113.476689. Epub 2013 Aug 7. J Biol Chem. 2013. PMID: 23926111 Free PMC article.

4

TFEB Overexpression in the P301S Model of Tauopathy Mitigates Increased PHF1 Levels and Lipofuscin Puncta and Rescues Memory Deficits.

Wang H, Wang R, Carrera I, Xu S, Lakshmana MK. Wang H, et al. Among authors: lakshmana mk. eNeuro. 2016 May 23;3(2):ENEURO.0042-16.2016. doi: 10.1523/ENEURO.0042-16.2016. eCollection 2016 Mar-Apr. eNeuro. 2016. PMID: 27257626 Free PMC article.

5

Role of RanBP9 on amyloidogenic processing of APP and synaptic protein levels in the mouse brain.

Lakshmana MK, Hayes CD, Bennett SP, Bianchi E, Reddy KM, Koo EH, Kang DE. Lakshmana MK, et al. FASEB J. 2012 May;26(5):2072-83. doi: 10.1096/fj.11-196709. Epub 2012 Jan 31. FASEB J. 2012. PMID: 22294787 Free PMC article.

6

Striking reduction of amyloid plaque burden in an Alzheimer's mouse model after chronic administration of carmustine.

Hayes CD, Dey D, Palavicini JP, Wang H, Patkar KA, Minond D, Nefzi A, Lakshmana MK. Hayes CD, et al. Among authors: lakshmana mk. BMC Med. 2013 Mar 26;11:81. doi: 10.1186/1741-7015-11-81. BMC Med. 2013. PMID: 23531149 Free PMC article.

7

Chronic cladribine administration increases amyloid beta peptide generation and plaque burden in mice.

Hayes CD, Dey D, Palavicini JP, Wang H, Araki W, Lakshmana MK. Hayes CD, et al. Among authors: lakshmana mk. PLoS One. 2012;7(10):e45841. doi: 10.1371/journal.pone.0045841. Epub 2012 Oct 3. PLoS One. 2012. PMID: 23056220 Free PMC article.

8

RanBP9 overexpression accelerates loss of pre and postsynaptic proteins in the APΔE9 transgenic mouse brain.

Wang H, Wang R, Xu S, Lakshmana MK. Wang H, et al. Among authors: lakshmana mk. PLoS One. 2014 Jan 14;9(1):e85484. doi: 10.1371/journal.pone.0085484. eCollection 2014. PLoS One. 2014. PMID: 24454876 Free PMC article.

9

RanBP9 aggravates synaptic damage in the mouse brain and is inversely correlated to spinophilin levels in Alzheimer's brain synaptosomes.

Palavicini JP, Wang H, Bianchi E, Xu S, Rao JS, Kang DE, Lakshmana MK. Palavicini JP, et al. Among authors: lakshmana mk. Cell Death Dis. 2013 Jun 13;4(6):e667. doi: 10.1038/cddis.2013.183. Cell Death Dis. 2013. PMID: 23764848 Free PMC article.

10

RanBP9 overexpression down-regulates phospho-cofilin, causes early synaptic deficits and impaired learning, and accelerates accumulation of amyloid plaques in the mouse brain.

Palavicini JP, Wang H, Minond D, Bianchi E, Xu S, Lakshmana MK. Palavicini JP, et al. Among authors: lakshmana mk. J Alzheimers Dis. 2014;39(4):727-40. doi: 10.3233/JAD-131550. J Alzheimers Dis. 2014. PMID: 24254706

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