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Inhibition of monoacylglycerol lipase, an anti-inflammatory and antifibrogenic strategy in the liver.
Habib A, Chokr D, Wan J, Hegde P, Mabire M, Siebert M, Ribeiro-Parenti L, Le Gall M, Lettéron P, Pilard N, Mansouri A, Brouillet A, Tardelli M, Weiss E, Le Faouder P, Guillou H, Cravatt BF, Moreau R, Trauner M, Lotersztajn S. Habib A, et al. Among authors: lotersztajn s. Gut. 2019 Mar;68(3):522-532. doi: 10.1136/gutjnl-2018-316137. Epub 2018 Oct 9. Gut. 2019. PMID: 30301768
Monoacylglycerol Lipase Inhibition Protects From Liver Injury in Mouse Models of Sclerosing Cholangitis.
Tardelli M, Bruschi FV, Fuchs CD, Claudel T, Auer N, Kunczer V, Baumgartner M, A H O Ronda O, Verkade HJ, Stojakovic T, Scharnagl H, Habib A, Zimmermann R, Lotersztajn S, Trauner M. Tardelli M, et al. Among authors: lotersztajn s. Hepatology. 2020 May;71(5):1750-1765. doi: 10.1002/hep.30929. Epub 2019 Dec 30. Hepatology. 2020. PMID: 31505038 Free PMC article.
Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target.
Smati S, Polizzi A, Fougerat A, Ellero-Simatos S, Blum Y, Lippi Y, Régnier M, Laroyenne A, Huillet M, Arif M, Zhang C, Lasserre F, Marrot A, Al Saati T, Wan J, Sommer C, Naylies C, Batut A, Lukowicz C, Fougeray T, Tramunt B, Dubot P, Smith L, Bertrand-Michel J, Hennuyer N, Pradere JP, Staels B, Burcelin R, Lenfant F, Arnal JF, Levade T, Gamet-Payrastre L, Lagarrigue S, Loiseau N, Lotersztajn S, Postic C, Wahli W, Bureau C, Guillaume M, Mardinoglu A, Montagner A, Gourdy P, Guillou H. Smati S, et al. Among authors: lotersztajn s. Gut. 2022 Apr;71(4):807-821. doi: 10.1136/gutjnl-2020-323323. Epub 2021 Apr 26. Gut. 2022. PMID: 33903148 Free article.
Monoacylglycerol lipase reprograms hepatocytes and macrophages to promote liver regeneration.
Allaire M, Al Sayegh R, Mabire M, Hammoutene A, Siebert M, Caër C, Cadoux M, Wan J, Habib A, Le Gall M, de la Grange P, Guillou H, Postic C, Paradis V, Lotersztajn S, Gilgenkrantz H. Allaire M, et al. Among authors: lotersztajn s. JHEP Rep. 2023 May 16;5(8):100794. doi: 10.1016/j.jhepr.2023.100794. eCollection 2023 Aug. JHEP Rep. 2023. PMID: 37520673 Free PMC article.
138 results