Hubbi ME - Search Results

1

Control of the interface between heterotypic cell populations reveals the mechanism of intercellular transfer of signaling proteins.

Kshitiz, Afzal J, Suhail Y, Ahn EH, Goyal R, Hubbi ME, Hussaini Q, Ellison DD, Goyal J, Nacev B, Kim DH, Lee JH, Frankel S, Gray K, Bankoti R, Chien AJ, Levchenko A. Kshitiz, et al. Among authors: hubbi me. Integr Biol (Camb). 2015 Mar;7(3):364-72. doi: 10.1039/c4ib00209a. Integr Biol (Camb). 2015. PMID: 25784457 Free PMC article.

2

Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors.

Kshitiz, Hubbi ME, Ahn EH, Downey J, Afzal J, Kim DH, Rey S, Chang C, Kundu A, Semenza GL, Abraham RM, Levchenko A. Kshitiz, et al. Among authors: hubbi me. Sci Signal. 2012 Jun 5;5(227):ra41. doi: 10.1126/scisignal.2003002. Sci Signal. 2012. PMID: 22669846 Free PMC article.

3

A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication.

Hubbi ME, Kshitiz, Gilkes DM, Rey S, Wong CC, Luo W, Kim DH, Dang CV, Levchenko A, Semenza GL. Hubbi ME, et al. Sci Signal. 2013 Feb 12;6(262):ra10. doi: 10.1126/scisignal.2003417. Sci Signal. 2013. PMID: 23405012 Free PMC article.

4

Chaperone-mediated autophagy targets hypoxia-inducible factor-1α (HIF-1α) for lysosomal degradation.

Hubbi ME, Hu H, Kshitiz, Ahmed I, Levchenko A, Semenza GL. Hubbi ME, et al. J Biol Chem. 2013 Apr 12;288(15):10703-14. doi: 10.1074/jbc.M112.414771. Epub 2013 Mar 1. J Biol Chem. 2013. PMID: 23457305 Free PMC article.

5

Lactate-dependent chaperone-mediated autophagy induces oscillatory HIF-1α activity promoting proliferation of hypoxic cells.

Kshitiz, Afzal J, Suhail Y, Chang H, Hubbi ME, Hamidzadeh A, Goyal R, Liu Y, Sun P, Nicoli S, Dang CV, Levchenko A. Kshitiz, et al. Among authors: hubbi me. Cell Syst. 2022 Dec 21;13(12):1048-1064.e7. doi: 10.1016/j.cels.2022.11.003. Epub 2022 Dec 2. Cell Syst. 2022. PMID: 36462504 Free PMC article.

6

Sirtuin-7 inhibits the activity of hypoxia-inducible factors.

Hubbi ME, Hu H, Kshitiz, Gilkes DM, Semenza GL. Hubbi ME, et al. J Biol Chem. 2013 Jul 19;288(29):20768-20775. doi: 10.1074/jbc.M113.476903. Epub 2013 Jun 9. J Biol Chem. 2013. PMID: 23750001 Free PMC article.

7

Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression.

Hubbi ME, Gilkes DM, Hu H, Kshitiz, Ahmed I, Semenza GL. Hubbi ME, et al. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3325-34. doi: 10.1073/pnas.1412840111. Epub 2014 Jul 28. Proc Natl Acad Sci U S A. 2014. PMID: 25071185 Free PMC article.

8

Spermidine/spermine-N1-acetyltransferase 2 is an essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1alpha.

Baek JH, Liu YV, McDonald KR, Wesley JB, Hubbi ME, Byun H, Semenza GL. Baek JH, et al. Among authors: hubbi me. J Biol Chem. 2007 Aug 10;282(32):23572-80. doi: 10.1074/jbc.M703504200. Epub 2007 Jun 8. J Biol Chem. 2007. PMID: 17558023 Free article.

9

Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization.

Liu YV, Hubbi ME, Pan F, McDonald KR, Mansharamani M, Cole RN, Liu JO, Semenza GL. Liu YV, et al. Among authors: hubbi me. J Biol Chem. 2007 Dec 21;282(51):37064-73. doi: 10.1074/jbc.M705015200. Epub 2007 Oct 26. J Biol Chem. 2007. PMID: 17965024 Free PMC article.

10

MCM proteins are negative regulators of hypoxia-inducible factor 1.

Hubbi ME, Luo W, Baek JH, Semenza GL. Hubbi ME, et al. Mol Cell. 2011 Jun 10;42(5):700-12. doi: 10.1016/j.molcel.2011.03.029. Mol Cell. 2011. PMID: 21658608 Free PMC article.

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