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Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients.
Holter JC, Pischke SE, de Boer E, Lind A, Jenum S, Holten AR, Tonby K, Barratt-Due A, Sokolova M, Schjalm C, Chaban V, Kolderup A, Tran T, Tollefsrud Gjølberg T, Skeie LG, Hesstvedt L, Ormåsen V, Fevang B, Austad C, Müller KE, Fladeby C, Holberg-Petersen M, Halvorsen B, Müller F, Aukrust P, Dudman S, Ueland T, Andersen JT, Lund-Johansen F, Heggelund L, Dyrhol-Riise AM, Mollnes TE. Holter JC, et al. Among authors: holberg petersen m. Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):25018-25025. doi: 10.1073/pnas.2010540117. Epub 2020 Sep 17. Proc Natl Acad Sci U S A. 2020. PMID: 32943538 Free PMC article.
Persistent pulmonary pathology after COVID-19 is associated with high viral load, weak antibody response, and high levels of matrix metalloproteinase-9.
Lerum TV, Maltzahn NN, Aukrust P, Trøseid M, Henriksen KN, Kåsine T, Dyrhol-Riise AM, Stiksrud B, Haugli M, Blomberg B, Kittang BR, Johannessen A, Hannula R, Aballi S, Kildal AB, Eiken R, Dahl TB, Lund-Johansen F, Müller F, Rodriguez JR, Meltzer C, Einvik G, Ueland T, Olsen IC; NOR-SOLIDARITY Consortium; Barratt-Due A, Aaløkken TM, Skjønsberg OH. Lerum TV, et al. Sci Rep. 2021 Dec 1;11(1):23205. doi: 10.1038/s41598-021-02547-x. Sci Rep. 2021. PMID: 34853380 Free PMC article. Clinical Trial.
Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial.
Barratt-Due A, Olsen IC, Nezvalova-Henriksen K, Kåsine T, Lund-Johansen F, Hoel H, Holten AR, Tveita A, Mathiessen A, Haugli M, Eiken R, Kildal AB, Berg Å, Johannessen A, Heggelund L, Dahl TB, Skåra KH, Mielnik P, Le LAK, Thoresen L, Ernst G, Hoff DAL, Skudal H, Kittang BR, Olsen RB, Tholin B, Ystrøm CM, Skei NV, Tran T, Dudman S, Andersen JT, Hannula R, Dalgard O, Finbråten AK, Tonby K, Blomberg B, Aballi S, Fladeby C, Steffensen A, Müller F, Dyrhol-Riise AM, Trøseid M, Aukrust P; NOR-Solidarity trial. Barratt-Due A, et al. Ann Intern Med. 2021 Sep;174(9):1261-1269. doi: 10.7326/M21-0653. Epub 2021 Jul 13. Ann Intern Med. 2021. PMID: 34251903 Free PMC article. Clinical Trial.
Breakthrough infections with the omicron and delta variants of SARS-CoV-2 result in similar re-activation of vaccine-induced immunity.
Søraas A, Grødeland G, Granerud BK, Ueland T, Lind A, Fevang B, Murphy SL, Huse C, Nygaard AB, Steffensen AK, Al-Baldawi H, Holberg-Petersen M, Andresen LL, Ågnes C, Ranheim T, Schanke Y, Istre M, Dahl JA, Chopra A, Dudman S, Kaarbø M, Andersen JT, Vaage EB, Tran TT, Vaage JT, Michelsen AE, Müller F, Aukrust P, Halvorsen B, Dahl TB, Holter JC, Lund-Johansen F. Søraas A, et al. Among authors: holberg petersen m. Front Immunol. 2022 Sep 8;13:964525. doi: 10.3389/fimmu.2022.964525. eCollection 2022. Front Immunol. 2022. PMID: 36159859 Free PMC article.
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