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A voltage-gated calcium channel regulates lysosomal fusion with endosomes and autophagosomes and is required for neuronal homeostasis.
Tian X, Gala U, Zhang Y, Shang W, Nagarkar Jaiswal S, di Ronza A, Jaiswal M, Yamamoto S, Sandoval H, Duraine L, Sardiello M, Sillitoe RV, Venkatachalam K, Fan H, Bellen HJ, Tong C. Tian X, et al. Among authors: venkatachalam k. PLoS Biol. 2015 Mar 26;13(3):e1002103. doi: 10.1371/journal.pbio.1002103. eCollection 2015 Mar. PLoS Biol. 2015. PMID: 25811491 Free PMC article.
Drosophila TRPML is required for TORC1 activation.
Wong CO, Li R, Montell C, Venkatachalam K. Wong CO, et al. Among authors: venkatachalam k. Curr Biol. 2012 Sep 11;22(17):1616-21. doi: 10.1016/j.cub.2012.06.055. Epub 2012 Aug 2. Curr Biol. 2012. PMID: 22863314 Free PMC article.
The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration.
Wang S, Tan KL, Agosto MA, Xiong B, Yamamoto S, Sandoval H, Jaiswal M, Bayat V, Zhang K, Charng WL, David G, Duraine L, Venkatachalam K, Wensel TG, Bellen HJ. Wang S, et al. Among authors: venkatachalam k. PLoS Biol. 2014 Apr 29;12(4):e1001847. doi: 10.1371/journal.pbio.1001847. eCollection 2014 Apr. PLoS Biol. 2014. PMID: 24781186 Free PMC article.
A TRPV channel in Drosophila motor neurons regulates presynaptic resting Ca2+ levels, synapse growth, and synaptic transmission.
Wong CO, Chen K, Lin YQ, Chao Y, Duraine L, Lu Z, Yoon WH, Sullivan JM, Broadhead GT, Sumner CJ, Lloyd TE, Macleod GT, Bellen HJ, Venkatachalam K. Wong CO, et al. Among authors: venkatachalam k. Neuron. 2014 Nov 19;84(4):764-77. doi: 10.1016/j.neuron.2014.09.030. Epub 2014 Oct 30. Neuron. 2014. PMID: 25451193 Free PMC article.
Correction: the retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration.
Wang S, Tan KL, Agosto MA, Xiong B, Yamamoto S, Sandoval H, Jaiswal M, Bayat V, Zhang K, Charng WL, David G, Duraine L, Venkatachalam K, Wensel TG, Bellen HJ. Wang S, et al. Among authors: venkatachalam k. PLoS Biol. 2015 May 28;13(5):e1002170. doi: 10.1371/journal.pbio.1002170. eCollection 2015 May. PLoS Biol. 2015. PMID: 26020534 Free PMC article.
Low doses of the neonicotinoid insecticide imidacloprid induce ROS triggering neurological and metabolic impairments in Drosophila.
Martelli F, Zhongyuan Z, Wang J, Wong CO, Karagas NE, Roessner U, Rupasinghe T, Venkatachalam K, Perry T, Bellen HJ, Batterham P. Martelli F, et al. Among authors: venkatachalam k. Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25840-25850. doi: 10.1073/pnas.2011828117. Epub 2020 Sep 28. Proc Natl Acad Sci U S A. 2020. PMID: 32989137 Free PMC article.
215 results