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CO-Releasing Molecules Have Nonheme Targets in Bacteria: Transcriptomic, Mathematical Modeling and Biochemical Analyses of CORM-3 [Ru(CO)3Cl(glycinate)] Actions on a Heme-Deficient Mutant of Escherichia coli.
Wilson JL, Wareham LK, McLean S, Begg R, Greaves S, Mann BE, Sanguinetti G, Poole RK. Wilson JL, et al. Among authors: begg r. Antioxid Redox Signal. 2015 Jul 10;23(2):148-62. doi: 10.1089/ars.2014.6151. Epub 2015 Apr 28. Antioxid Redox Signal. 2015. PMID: 25811604 Free PMC article.
Analysis of the bacterial response to Ru(CO)3Cl(Glycinate) (CORM-3) and the inactivated compound identifies the role played by the ruthenium compound and reveals sulfur-containing species as a major target of CORM-3 action.
McLean S, Begg R, Jesse HE, Mann BE, Sanguinetti G, Poole RK. McLean S, et al. Among authors: begg r. Antioxid Redox Signal. 2013 Dec 10;19(17):1999-2012. doi: 10.1089/ars.2012.5103. Epub 2013 Apr 16. Antioxid Redox Signal. 2013. PMID: 23472713 Free PMC article.
Carbon Monoxide Gas Is Not Inert, but Global, in Its Consequences for Bacterial Gene Expression, Iron Acquisition, and Antibiotic Resistance.
Wareham LK, Begg R, Jesse HE, Van Beilen JW, Ali S, Svistunenko D, McLean S, Hellingwerf KJ, Sanguinetti G, Poole RK. Wareham LK, et al. Among authors: begg r. Antioxid Redox Signal. 2016 Jun 10;24(17):1013-28. doi: 10.1089/ars.2015.6501. Epub 2016 Mar 30. Antioxid Redox Signal. 2016. PMID: 26907100 Free PMC article.
The Broad-Spectrum Antimicrobial Potential of [Mn(CO)4(S2CNMe(CH2CO2H))], a Water-Soluble CO-Releasing Molecule (CORM-401): Intracellular Accumulation, Transcriptomic and Statistical Analyses, and Membrane Polarization.
Wareham LK, McLean S, Begg R, Rana N, Ali S, Kendall JJ, Sanguinetti G, Mann BE, Poole RK. Wareham LK, et al. Among authors: begg r. Antioxid Redox Signal. 2018 May 10;28(14):1286-1308. doi: 10.1089/ars.2017.7239. Epub 2017 Sep 28. Antioxid Redox Signal. 2018. PMID: 28816060 Free PMC article.
185 results