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CO-Releasing Molecules Have Nonheme Targets in Bacteria: Transcriptomic, Mathematical Modeling and Biochemical Analyses of CORM-3 [Ru(CO)3Cl(glycinate)] Actions on a Heme-Deficient Mutant of Escherichia coli.
Wilson JL, Wareham LK, McLean S, Begg R, Greaves S, Mann BE, Sanguinetti G, Poole RK. Wilson JL, et al. Among authors: mclean s. Antioxid Redox Signal. 2015 Jul 10;23(2):148-62. doi: 10.1089/ars.2014.6151. Epub 2015 Apr 28. Antioxid Redox Signal. 2015. PMID: 25811604 Free PMC article.
Analysis of the bacterial response to Ru(CO)3Cl(Glycinate) (CORM-3) and the inactivated compound identifies the role played by the ruthenium compound and reveals sulfur-containing species as a major target of CORM-3 action.
McLean S, Begg R, Jesse HE, Mann BE, Sanguinetti G, Poole RK. McLean S, et al. Antioxid Redox Signal. 2013 Dec 10;19(17):1999-2012. doi: 10.1089/ars.2012.5103. Epub 2013 Apr 16. Antioxid Redox Signal. 2013. PMID: 23472713 Free PMC article.
Cytochrome bd-I in Escherichia coli is less sensitive than cytochromes bd-II or bo'' to inhibition by the carbon monoxide-releasing molecule, CORM-3: N-acetylcysteine reduces CO-RM uptake and inhibition of respiration.
Jesse HE, Nye TL, McLean S, Green J, Mann BE, Poole RK. Jesse HE, et al. Among authors: mclean s. Biochim Biophys Acta. 2013 Sep;1834(9):1693-703. doi: 10.1016/j.bbapap.2013.04.019. Epub 2013 Apr 26. Biochim Biophys Acta. 2013. PMID: 23624261 Free PMC article.
Interaction of the carbon monoxide-releasing molecule Ru(CO)3Cl(glycinate) (CORM-3) with Salmonella enterica serovar Typhimurium: in situ measurements of carbon monoxide binding by integrating cavity dual-beam spectrophotometry.
Rana N, McLean S, Mann BE, Poole RK. Rana N, et al. Among authors: mclean s. Microbiology (Reading). 2014 Dec;160(Pt 12):2771-2779. doi: 10.1099/mic.0.081042-0. Epub 2014 Aug 1. Microbiology (Reading). 2014. PMID: 25085864 Free article.
Carbon Monoxide Gas Is Not Inert, but Global, in Its Consequences for Bacterial Gene Expression, Iron Acquisition, and Antibiotic Resistance.
Wareham LK, Begg R, Jesse HE, Van Beilen JW, Ali S, Svistunenko D, McLean S, Hellingwerf KJ, Sanguinetti G, Poole RK. Wareham LK, et al. Among authors: mclean s. Antioxid Redox Signal. 2016 Jun 10;24(17):1013-28. doi: 10.1089/ars.2015.6501. Epub 2016 Mar 30. Antioxid Redox Signal. 2016. PMID: 26907100 Free PMC article.
The Broad-Spectrum Antimicrobial Potential of [Mn(CO)4(S2CNMe(CH2CO2H))], a Water-Soluble CO-Releasing Molecule (CORM-401): Intracellular Accumulation, Transcriptomic and Statistical Analyses, and Membrane Polarization.
Wareham LK, McLean S, Begg R, Rana N, Ali S, Kendall JJ, Sanguinetti G, Mann BE, Poole RK. Wareham LK, et al. Among authors: mclean s. Antioxid Redox Signal. 2018 May 10;28(14):1286-1308. doi: 10.1089/ars.2017.7239. Epub 2017 Sep 28. Antioxid Redox Signal. 2018. PMID: 28816060 Free PMC article.
Nitrosothiols in bacterial pathogens and pathogenesis.
Laver JR, McLean S, Bowman LA, Harrison LJ, Read RC, Poole RK. Laver JR, et al. Among authors: mclean s. Antioxid Redox Signal. 2013 Jan 20;18(3):309-22. doi: 10.1089/ars.2012.4767. Epub 2012 Aug 22. Antioxid Redox Signal. 2013. PMID: 22768799 Review.
1,149 results