Lin HK - Search Results

1

Skp2-macroH2A1-CDK8 axis orchestrates G2/M transition and tumorigenesis.

Xu D, Li CF, Zhang X, Gong Z, Chan CH, Lee SW, Jin G, Rezaeian AH, Han F, Wang J, Yang WL, Feng ZZ, Chen W, Wu CY, Wang YJ, Chow LP, Zhu XF, Zeng YX, Lin HK. Xu D, et al. Among authors: lin hk. Nat Commun. 2015 Mar 30;6:6641. doi: 10.1038/ncomms7641. Nat Commun. 2015. PMID: 25818643 Free PMC article.

2

Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB.

Lin HK, Wang G, Chen Z, Teruya-Feldstein J, Liu Y, Chan CH, Yang WL, Erdjument-Bromage H, Nakayama KI, Nimer S, Tempst P, Pandolfi PP. Lin HK, et al. Nat Cell Biol. 2009 Apr;11(4):420-32. doi: 10.1038/ncb1849. Epub 2009 Mar 8. Nat Cell Biol. 2009. PMID: 19270694 Free PMC article.

3

The E3 ligase TRAF6 regulates Akt ubiquitination and activation.

Yang WL, Wang J, Chan CH, Lee SW, Campos AD, Lamothe B, Hur L, Grabiner BC, Lin X, Darnay BG, Lin HK. Yang WL, et al. Among authors: lin hk, lin x. Science. 2009 Aug 28;325(5944):1134-8. doi: 10.1126/science.1175065. Science. 2009. PMID: 19713527 Free PMC article.

4

Regulation of Akt signaling activation by ubiquitination.

Yang WL, Wu CY, Wu J, Lin HK. Yang WL, et al. Among authors: lin hk. Cell Cycle. 2010 Feb 1;9(3):487-97. doi: 10.4161/cc.9.3.10508. Cell Cycle. 2010. PMID: 20081374 Free PMC article. Review.

5

Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence.

Lin HK, Chen Z, Wang G, Nardella C, Lee SW, Chan CH, Yang WL, Wang J, Egia A, Nakayama KI, Cordon-Cardo C, Teruya-Feldstein J, Pandolfi PP. Lin HK, et al. Nature. 2010 Mar 18;464(7287):374-9. doi: 10.1038/nature08815. Nature. 2010. PMID: 20237562 Free PMC article.

6

Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis.

Chan CH, Lee SW, Li CF, Wang J, Yang WL, Wu CY, Wu J, Nakayama KI, Kang HY, Huang HY, Hung MC, Pandolfi PP, Lin HK. Chan CH, et al. Among authors: lin hk. Nat Cell Biol. 2010 May;12(5):457-67. doi: 10.1038/ncb2047. Epub 2010 Apr 11. Nat Cell Biol. 2010. PMID: 20383141 Free PMC article.

7

Regulation of Skp2 expression and activity and its role in cancer progression.

Chan CH, Lee SW, Wang J, Lin HK. Chan CH, et al. Among authors: lin hk. ScientificWorldJournal. 2010 Jun 1;10:1001-15. doi: 10.1100/tsw.2010.89. ScientificWorldJournal. 2010. PMID: 20526532 Free PMC article. Review.

8

ER stress inhibits mTORC2 and Akt signaling through GSK-3β-mediated phosphorylation of rictor.

Chen CH, Shaikenov T, Peterson TR, Aimbetov R, Bissenbaev AK, Lee SW, Wu J, Lin HK, Sarbassov dos D. Chen CH, et al. Among authors: lin hk. Sci Signal. 2011 Feb 22;4(161):ra10. doi: 10.1126/scisignal.2001731. Sci Signal. 2011. PMID: 21343617

9

Novel ARF/p53-independent senescence pathways in cancer repression.

Chan CH, Gao Y, Moten A, Lin HK. Chan CH, et al. Among authors: lin hk. J Mol Med (Berl). 2011 Sep;89(9):857-67. doi: 10.1007/s00109-011-0766-y. Epub 2011 May 19. J Mol Med (Berl). 2011. PMID: 21594579 Free PMC article. Review.

10

Critical role of monoubiquitination of histone H2AX protein in histone H2AX phosphorylation and DNA damage response.

Wu CY, Kang HY, Yang WL, Wu J, Jeong YS, Wang J, Chan CH, Lee SW, Zhang X, Lamothe B, Campos AD, Darnay BG, Lin HK. Wu CY, et al. Among authors: lin hk. J Biol Chem. 2011 Sep 2;286(35):30806-30815. doi: 10.1074/jbc.M111.257469. Epub 2011 Jun 20. J Biol Chem. 2011. PMID: 21690091 Free PMC article.

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