Yang WL - Search Results

1

Skp2-macroH2A1-CDK8 axis orchestrates G2/M transition and tumorigenesis.

Xu D, Li CF, Zhang X, Gong Z, Chan CH, Lee SW, Jin G, Rezaeian AH, Han F, Wang J, Yang WL, Feng ZZ, Chen W, Wu CY, Wang YJ, Chow LP, Zhu XF, Zeng YX, Lin HK. Xu D, et al. Among authors: yang wl. Nat Commun. 2015 Mar 30;6:6641. doi: 10.1038/ncomms7641. Nat Commun. 2015. PMID: 25818643 Free PMC article.

2

Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence.

Lin HK, Chen Z, Wang G, Nardella C, Lee SW, Chan CH, Yang WL, Wang J, Egia A, Nakayama KI, Cordon-Cardo C, Teruya-Feldstein J, Pandolfi PP. Lin HK, et al. Among authors: yang wl. Nature. 2010 Mar 18;464(7287):374-9. doi: 10.1038/nature08815. Nature. 2010. PMID: 20237562 Free PMC article.

3

Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis.

Chan CH, Lee SW, Li CF, Wang J, Yang WL, Wu CY, Wu J, Nakayama KI, Kang HY, Huang HY, Hung MC, Pandolfi PP, Lin HK. Chan CH, et al. Among authors: yang wl. Nat Cell Biol. 2010 May;12(5):457-67. doi: 10.1038/ncb2047. Epub 2010 Apr 11. Nat Cell Biol. 2010. PMID: 20383141 Free PMC article.

4

The role of Skp2 in hematopoietic stem cell quiescence, pool size, and self-renewal.

Wang J, Han F, Wu J, Lee SW, Chan CH, Wu CY, Yang WL, Gao Y, Zhang X, Jeong YS, Moten A, Samaniego F, Huang P, Liu Q, Zeng YX, Lin HK. Wang J, et al. Among authors: yang wl. Blood. 2011 Nov 17;118(20):5429-38. doi: 10.1182/blood-2010-10-312785. Epub 2011 Sep 19. Blood. 2011. PMID: 21931116 Free PMC article.

5

The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis.

Chan CH, Li CF, Yang WL, Gao Y, Lee SW, Feng Z, Huang HY, Tsai KK, Flores LG, Shao Y, Hazle JD, Yu D, Wei W, Sarbassov D, Hung MC, Nakayama KI, Lin HK. Chan CH, et al. Among authors: yang wl. Cell. 2012 May 25;149(5):1098-111. doi: 10.1016/j.cell.2012.02.065. Cell. 2012. PMID: 22632973 Free PMC article.

6

Skp2-dependent ubiquitination and activation of LKB1 is essential for cancer cell survival under energy stress.

Lee SW, Li CF, Jin G, Cai Z, Han F, Chan CH, Yang WL, Li BK, Rezaeian AH, Li HY, Huang HY, Lin HK. Lee SW, et al. Among authors: yang wl. Mol Cell. 2015 Mar 19;57(6):1022-1033. doi: 10.1016/j.molcel.2015.01.015. Epub 2015 Feb 26. Mol Cell. 2015. PMID: 25728766 Free PMC article.

7

Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB.

Lin HK, Wang G, Chen Z, Teruya-Feldstein J, Liu Y, Chan CH, Yang WL, Erdjument-Bromage H, Nakayama KI, Nimer S, Tempst P, Pandolfi PP. Lin HK, et al. Among authors: yang wl. Nat Cell Biol. 2009 Apr;11(4):420-32. doi: 10.1038/ncb1849. Epub 2009 Mar 8. Nat Cell Biol. 2009. PMID: 19270694 Free PMC article.

8

The E3 ligase TRAF6 regulates Akt ubiquitination and activation.

Yang WL, Wang J, Chan CH, Lee SW, Campos AD, Lamothe B, Hur L, Grabiner BC, Lin X, Darnay BG, Lin HK. Yang WL, et al. Science. 2009 Aug 28;325(5944):1134-8. doi: 10.1126/science.1175065. Science. 2009. PMID: 19713527 Free PMC article.

9

Regulation of Akt signaling activation by ubiquitination.

Yang WL, Wu CY, Wu J, Lin HK. Yang WL, et al. Cell Cycle. 2010 Feb 1;9(3):487-97. doi: 10.4161/cc.9.3.10508. Cell Cycle. 2010. PMID: 20081374 Free PMC article. Review.

10

Critical role of monoubiquitination of histone H2AX protein in histone H2AX phosphorylation and DNA damage response.

Wu CY, Kang HY, Yang WL, Wu J, Jeong YS, Wang J, Chan CH, Lee SW, Zhang X, Lamothe B, Campos AD, Darnay BG, Lin HK. Wu CY, et al. Among authors: yang wl. J Biol Chem. 2011 Sep 2;286(35):30806-30815. doi: 10.1074/jbc.M111.257469. Epub 2011 Jun 20. J Biol Chem. 2011. PMID: 21690091 Free PMC article.

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