Sethi G - Search Results

1

Isorhamnetin augments the anti-tumor effect of capecitabine through the negative regulation of NF-κB signaling cascade in gastric cancer.

Manu KA, Shanmugam MK, Ramachandran L, Li F, Siveen KS, Chinnathambi A, Zayed ME, Alharbi SA, Arfuso F, Kumar AP, Ahn KS, Sethi G. Manu KA, et al. Among authors: sethi g. Cancer Lett. 2015 Jul 10;363(1):28-36. doi: 10.1016/j.canlet.2015.03.033. Epub 2015 Mar 28. Cancer Lett. 2015. PMID: 25827070

2

TNF blockade: an inflammatory issue.

Aggarwal BB, Shishodia S, Takada Y, Jackson-Bernitsas D, Ahn KS, Sethi G, Ichikawa H. Aggarwal BB, et al. Among authors: sethi g. Ernst Schering Res Found Workshop. 2006;(56):161-86. doi: 10.1007/3-540-37673-9_10. Ernst Schering Res Found Workshop. 2006. PMID: 16331857 Review.

3

Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherapeutic agents.

Sandur SK, Ichikawa H, Sethi G, Ahn KS, Aggarwal BB. Sandur SK, et al. Among authors: sethi g. J Biol Chem. 2006 Jun 23;281(25):17023-17033. doi: 10.1074/jbc.M601595200. Epub 2006 Apr 19. J Biol Chem. 2006. PMID: 16624823 Free article.

4

Genetic deletion of NAD(P)H:quinone oxidoreductase 1 abrogates activation of nuclear factor-kappaB, IkappaBalpha kinase, c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and potentiates apoptosis.

Ahn KS, Sethi G, Jain AK, Jaiswal AK, Aggarwal BB. Ahn KS, et al. Among authors: sethi g. J Biol Chem. 2006 Jul 21;281(29):19798-808. doi: 10.1074/jbc.M601162200. Epub 2006 May 8. J Biol Chem. 2006. PMID: 16682409 Free article.

5

Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-kappa B signaling pathway.

Sethi G, Ahn KS, Sandur SK, Lin X, Chaturvedi MM, Aggarwal BB. Sethi G, et al. J Biol Chem. 2006 Aug 18;281(33):23425-35. doi: 10.1074/jbc.M602627200. Epub 2006 Jun 19. J Biol Chem. 2006. PMID: 16785236 Free article.

6

Overexpression of tissue transglutaminase leads to constitutive activation of nuclear factor-kappaB in cancer cells: delineation of a novel pathway.

Mann AP, Verma A, Sethi G, Manavathi B, Wang H, Fok JY, Kunnumakkara AB, Kumar R, Aggarwal BB, Mehta K. Mann AP, et al. Among authors: sethi g. Cancer Res. 2006 Sep 1;66(17):8788-95. doi: 10.1158/0008-5472.CAN-06-1457. Cancer Res. 2006. PMID: 16951195

7

Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kappaB activation pathway.

Ahn KS, Sethi G, Shishodia S, Sung B, Arbiser JL, Aggarwal BB. Ahn KS, et al. Among authors: sethi g. Mol Cancer Res. 2006 Sep;4(9):621-33. doi: 10.1158/1541-7786.MCR-06-0076. Mol Cancer Res. 2006. PMID: 16966432

8

Deguelin, an Akt inhibitor, suppresses IkappaBalpha kinase activation leading to suppression of NF-kappaB-regulated gene expression, potentiation of apoptosis, and inhibition of cellular invasion.

Nair AS, Shishodia S, Ahn KS, Kunnumakkara AB, Sethi G, Aggarwal BB. Nair AS, et al. Among authors: sethi g. J Immunol. 2006 Oct 15;177(8):5612-22. doi: 10.4049/jimmunol.177.8.5612. J Immunol. 2006. PMID: 17015749

9

Embelin, an inhibitor of X chromosome-linked inhibitor-of-apoptosis protein, blocks nuclear factor-kappaB (NF-kappaB) signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products.

Ahn KS, Sethi G, Aggarwal BB. Ahn KS, et al. Among authors: sethi g. Mol Pharmacol. 2007 Jan;71(1):209-19. doi: 10.1124/mol.106.028787. Epub 2006 Oct 6. Mol Pharmacol. 2007. PMID: 17028156

10

Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation.

Sethi G, Ahn KS, Pandey MK, Aggarwal BB. Sethi G, et al. Blood. 2007 Apr 1;109(7):2727-35. doi: 10.1182/blood-2006-10-050807. Blood. 2007. PMID: 17110449 Free article.

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