Itoh Y - Search Results

1

Histone H3 peptide based LSD1-selective inhibitors.

Kakizawa T, Ota Y, Itoh Y, Tsumoto H, Suzuki T. Kakizawa T, et al. Among authors: itoh y. Bioorg Med Chem Lett. 2015 May 1;25(9):1925-8. doi: 10.1016/j.bmcl.2015.03.030. Epub 2015 Mar 20. Bioorg Med Chem Lett. 2015. PMID: 25827526

2

Highly potent and selective histone deacetylase 6 inhibitors designed based on a small-molecular substrate.

Suzuki T, Kouketsu A, Itoh Y, Hisakawa S, Maeda S, Yoshida M, Nakagawa H, Miyata N. Suzuki T, et al. Among authors: itoh y. J Med Chem. 2006 Aug 10;49(16):4809-12. doi: 10.1021/jm060554y. J Med Chem. 2006. PMID: 16884291

3

Identification of a potent and stable antiproliferative agent by the prodrug formation of a thiolate histone deacetylase inhibitor.

Suzuki T, Hisakawa S, Itoh Y, Maruyama S, Kurotaki M, Nakagawa H, Miyata N. Suzuki T, et al. Among authors: itoh y. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1558-61. doi: 10.1016/j.bmcl.2006.12.117. Epub 2007 Jan 13. Bioorg Med Chem Lett. 2007. PMID: 17257837

4

Design, synthesis, and biological activity of folate receptor-targeted prodrugs of thiolate histone deacetylase inhibitors.

Suzuki T, Hisakawa S, Itoh Y, Suzuki N, Takahashi K, Kawahata M, Yamaguchi K, Nakagawa H, Miyata N. Suzuki T, et al. Among authors: itoh y. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4208-12. doi: 10.1016/j.bmcl.2007.05.040. Epub 2007 May 17. Bioorg Med Chem Lett. 2007. PMID: 17532630

5

Design, synthesis, structure--selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors.

Itoh Y, Suzuki T, Kouketsu A, Suzuki N, Maeda S, Yoshida M, Nakagawa H, Miyata N. Itoh Y, et al. J Med Chem. 2007 Nov 1;50(22):5425-38. doi: 10.1021/jm7009217. Epub 2007 Oct 11. J Med Chem. 2007. PMID: 17929798

6

Isoform-selective histone deacetylase inhibitors.

Itoh Y, Suzuki T, Miyata N. Itoh Y, et al. Curr Pharm Des. 2008;14(6):529-44. doi: 10.2174/138161208783885335. Curr Pharm Des. 2008. PMID: 18336298 Review.

7

Identification of G protein-coupled receptor 120-selective agonists derived from PPARgamma agonists.

Suzuki T, Igari S, Hirasawa A, Hata M, Ishiguro M, Fujieda H, Itoh Y, Hirano T, Nakagawa H, Ogura M, Makishima M, Tsujimoto G, Miyata N. Suzuki T, et al. Among authors: itoh y. J Med Chem. 2008 Dec 11;51(23):7640-4. doi: 10.1021/jm800970b. J Med Chem. 2008. PMID: 19007110

8

Synthesis and activity of N-oxalylglycine and its derivatives as Jumonji C-domain-containing histone lysine demethylase inhibitors.

Hamada S, Kim TD, Suzuki T, Itoh Y, Tsumoto H, Nakagawa H, Janknecht R, Miyata N. Hamada S, et al. Among authors: itoh y. Bioorg Med Chem Lett. 2009 May 15;19(10):2852-5. doi: 10.1016/j.bmcl.2009.03.098. Epub 2009 Mar 26. Bioorg Med Chem Lett. 2009. PMID: 19359167

9

Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of jumonji domain-containing protein 2 histone demethylase inhibitors.

Hamada S, Suzuki T, Mino K, Koseki K, Oehme F, Flamme I, Ozasa H, Itoh Y, Ogasawara D, Komaarashi H, Kato A, Tsumoto H, Nakagawa H, Hasegawa M, Sasaki R, Mizukami T, Miyata N. Hamada S, et al. Among authors: itoh y. J Med Chem. 2010 Aug 12;53(15):5629-38. doi: 10.1021/jm1003655. J Med Chem. 2010. PMID: 20684604

10

Development of target protein-selective degradation inducer for protein knockdown.

Itoh Y, Ishikawa M, Kitaguchi R, Sato S, Naito M, Hashimoto Y. Itoh Y, et al. Bioorg Med Chem. 2011 May 15;19(10):3229-41. doi: 10.1016/j.bmc.2011.03.057. Epub 2011 Mar 29. Bioorg Med Chem. 2011. PMID: 21515062

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