Plaitakis A - Search Results

1

Differential interaction of hGDH1 and hGDH2 with manganese: Implications for metabolism and toxicity.

Dimovasili C, Aschner M, Plaitakis A, Zaganas I. Dimovasili C, et al. Among authors: plaitakis a. Neurochem Int. 2015 Sep;88:60-5. doi: 10.1016/j.neuint.2015.03.004. Epub 2015 Mar 30. Neurochem Int. 2015. PMID: 25837286

2

Study of structure-function relationships in human glutamate dehydrogenases reveals novel molecular mechanisms for the regulation of the nerve tissue-specific (GLUD2) isoenzyme.

Plaitakis A, Spanaki C, Mastorodemos V, Zaganas I. Plaitakis A, et al. Neurochem Int. 2003 Sep-Oct;43(4-5):401-10. doi: 10.1016/s0197-0186(03)00028-7. Neurochem Int. 2003. PMID: 12742085

3

Mutations in human GLUD2 glutamate dehydrogenase affecting basal activity and regulation.

Kanavouras K, Borompokas N, Latsoudis H, Stagourakis A, Zaganas I, Plaitakis A. Kanavouras K, et al. Among authors: plaitakis a. J Neurochem. 2009 May;109 Suppl 1:167-73. doi: 10.1111/j.1471-4159.2009.05914.x. J Neurochem. 2009. PMID: 19393024 Free article.

4

The human GLUD2 glutamate dehydrogenase: localization and functional aspects.

Zaganas I, Kanavouras K, Mastorodemos V, Latsoudis H, Spanaki C, Plaitakis A. Zaganas I, et al. Among authors: plaitakis a. Neurochem Int. 2009 Jul-Aug;55(1-3):52-63. doi: 10.1016/j.neuint.2009.03.001. Epub 2009 Mar 13. Neurochem Int. 2009. PMID: 19428807

5

The complex regulation of human glud1 and glud2 glutamate dehydrogenases and its implications in nerve tissue biology.

Spanaki C, Zaganas I, Kounoupa Z, Plaitakis A. Spanaki C, et al. Among authors: plaitakis a. Neurochem Int. 2012 Sep;61(4):470-81. doi: 10.1016/j.neuint.2012.05.020. Epub 2012 May 30. Neurochem Int. 2012. PMID: 22658952

6

Expression of human GLUD2 glutamate dehydrogenase in human tissues: functional implications.

Zaganas I, Spanaki C, Plaitakis A. Zaganas I, et al. Among authors: plaitakis a. Neurochem Int. 2012 Sep;61(4):455-62. doi: 10.1016/j.neuint.2012.06.007. Epub 2012 Jun 16. Neurochem Int. 2012. PMID: 22709674

7

Side-chain interactions in the regulatory domain of human glutamate dehydrogenase determine basal activity and regulation.

Mastorodemos V, Kanavouras K, Sundaram S, Providaki M, Petraki Z, Kokkinidis M, Zaganas I, Logothetis DE, Plaitakis A. Mastorodemos V, et al. Among authors: plaitakis a. J Neurochem. 2015 Apr;133(1):73-82. doi: 10.1111/jnc.13019. Epub 2015 Jan 26. J Neurochem. 2015. PMID: 25620628 Free article.

8

Crystal structure of glutamate dehydrogenase 2, a positively selected novel human enzyme involved in brain biology and cancer pathophysiology.

Dimovasili C, Fadouloglou VE, Kefala A, Providaki M, Kotsifaki D, Kanavouras K, Sarrou I, Plaitakis A, Zaganas I, Kokkinidis M. Dimovasili C, et al. Among authors: plaitakis a. J Neurochem. 2021 May;157(3):802-815. doi: 10.1111/jnc.15296. Epub 2021 Jan 23. J Neurochem. 2021. PMID: 33421122 Free article.

9

Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme.

Zaganas I, Plaitakis A. Zaganas I, et al. Among authors: plaitakis a. J Biol Chem. 2002 Jul 19;277(29):26422-8. doi: 10.1074/jbc.M200022200. Epub 2002 Apr 11. J Biol Chem. 2002. PMID: 11950837 Free article.

10

Substitution of Ser for Arg-443 in the regulatory domain of human housekeeping (GLUD1) glutamate dehydrogenase virtually abolishes basal activity and markedly alters the activation of the enzyme by ADP and L-leucine.

Zaganas I, Spanaki C, Karpusas M, Plaitakis A. Zaganas I, et al. Among authors: plaitakis a. J Biol Chem. 2002 Nov 29;277(48):46552-8. doi: 10.1074/jbc.M208596200. Epub 2002 Sep 24. J Biol Chem. 2002. PMID: 12324473 Free article.

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