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HIF2a inhibitors for the treatment of VHL disease.
Metelo AM, Noonan H, Iliopoulos O. Metelo AM, et al. Among authors: iliopoulos o. Oncotarget. 2015 Sep 15;6(27):23036-7. doi: 10.18632/oncotarget.4564. Oncotarget. 2015. PMID: 26325097 Free PMC article. Review. No abstract available.
Glutaminase and poly(ADP-ribose) polymerase inhibitors suppress pyrimidine synthesis and VHL-deficient renal cancers.
Okazaki A, Gameiro PA, Christodoulou D, Laviollette L, Schneider M, Chaves F, Stemmer-Rachamimov A, Yazinski SA, Lee R, Stephanopoulos G, Zou L, Iliopoulos O. Okazaki A, et al. Among authors: iliopoulos o. J Clin Invest. 2017 May 1;127(5):1631-1645. doi: 10.1172/JCI87800. Epub 2017 Mar 27. J Clin Invest. 2017. PMID: 28346230 Free PMC article.
Nitrogen Trapping as a Therapeutic Strategy in Tumors with Mitochondrial Dysfunction.
Madala HR, Helenius IT, Zhou W, Mills E, Zhang Y, Liu Y, Metelo AM, Kelley ML, Punganuru S, Kim KB, Olenchock B, Rhee E, Intlekofer AM, Iliopoulos O, Chouchani E, Yeh JJ. Madala HR, et al. Among authors: iliopoulos o. Cancer Res. 2020 Sep 1;80(17):3492-3506. doi: 10.1158/0008-5472.CAN-20-0246. Epub 2020 Jul 10. Cancer Res. 2020. PMID: 32651261 Free PMC article.
NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism.
Allouche J, Rachmin I, Adhikari K, Pardo LM, Lee JH, McConnell AM, Kato S, Fan S, Kawakami A, Suita Y, Wakamatsu K, Igras V, Zhang J, Navarro PP, Lugo CM, Noonan HR, Christie KA, Itin K, Mujahid N, Lo JA, Won CH, Evans CL, Weng QY, Wang H, Osseiran S, Lovas A, Németh I, Cozzio A, Navarini AA, Hsiao JJ, Nguyen N, Kemény LV, Iliopoulos O, Berking C, Ruzicka T, Gonzalez-José R, Bortolini MC, Canizales-Quinteros S, Acuna-Alonso V, Gallo C, Poletti G, Bedoya G, Rothhammer F, Ito S, Schiaffino MV, Chao LH, Kleinstiver BP, Tishkoff S, Zon LI, Nijsten T, Ruiz-Linares A, Fisher DE, Roider E. Allouche J, et al. Among authors: iliopoulos o. Cell. 2021 Aug 5;184(16):4268-4283.e20. doi: 10.1016/j.cell.2021.06.022. Epub 2021 Jul 6. Cell. 2021. PMID: 34233163 Free PMC article.
Evaluation, diagnosis and surveillance of renal masses in the setting of VHL disease.
Chahoud J, McGettigan M, Parikh N, Boris RS, Iliopoulos O, Rathmell WK, Daniels AB, Jonasch E, Spiess PE; International VHL Surveillance Guidelines Consortium-Renal Committee. Chahoud J, et al. Among authors: iliopoulos o. World J Urol. 2021 Jul;39(7):2409-2415. doi: 10.1007/s00345-020-03441-3. Epub 2020 Sep 16. World J Urol. 2021. PMID: 32936333 Free PMC article. Review.
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia.
Metallo CM, Gameiro PA, Bell EL, Mattaini KR, Yang J, Hiller K, Jewell CM, Johnson ZR, Irvine DJ, Guarente L, Kelleher JK, Vander Heiden MG, Iliopoulos O, Stephanopoulos G. Metallo CM, et al. Among authors: iliopoulos o. Nature. 2011 Nov 20;481(7381):380-4. doi: 10.1038/nature10602. Nature. 2011. PMID: 22101433 Free PMC article.
72 results