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An analysis of gene expression in PTSD implicates genes involved in the glucocorticoid receptor pathway and neural responses to stress.
Logue MW, Smith AK, Baldwin C, Wolf EJ, Guffanti G, Ratanatharathorn A, Stone A, Schichman SA, Humphries D, Binder EB, Arloth J, Menke A, Uddin M, Wildman D, Galea S, Aiello AE, Koenen KC, Miller MW. Logue MW, et al. Among authors: menke a. Psychoneuroendocrinology. 2015 Jul;57:1-13. doi: 10.1016/j.psyneuen.2015.03.016. Epub 2015 Mar 24. Psychoneuroendocrinology. 2015. PMID: 25867994 Free PMC article.
Gene expression studies in major depression.
Mehta D, Menke A, Binder EB. Mehta D, et al. Among authors: menke a. Curr Psychiatry Rep. 2010 Apr;12(2):135-44. doi: 10.1007/s11920-010-0100-3. Curr Psychiatry Rep. 2010. PMID: 20425299 Free PMC article. Review.
Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients.
Menke A, Arloth J, Pütz B, Weber P, Klengel T, Mehta D, Gonik M, Rex-Haffner M, Rubel J, Uhr M, Lucae S, Deussing JM, Müller-Myhsok B, Holsboer F, Binder EB. Menke A, et al. Neuropsychopharmacology. 2012 May;37(6):1455-64. doi: 10.1038/npp.2011.331. Epub 2012 Jan 11. Neuropsychopharmacology. 2012. PMID: 22237309 Free PMC article.
Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling.
Zannas AS, Arloth J, Carrillo-Roa T, Iurato S, Röh S, Ressler KJ, Nemeroff CB, Smith AK, Bradley B, Heim C, Menke A, Lange JF, Brückl T, Ising M, Wray NR, Erhardt A, Binder EB, Mehta D. Zannas AS, et al. Among authors: menke a. Genome Biol. 2015 Dec 17;16:266. doi: 10.1186/s13059-015-0828-5. Genome Biol. 2015. PMID: 26673150 Free PMC article.
Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies.
Mehta D, Gonik M, Klengel T, Rex-Haffner M, Menke A, Rubel J, Mercer KB, Pütz B, Bradley B, Holsboer F, Ressler KJ, Müller-Myhsok B, Binder EB. Mehta D, et al. Among authors: menke a. Arch Gen Psychiatry. 2011 Sep;68(9):901-10. doi: 10.1001/archgenpsychiatry.2011.50. Epub 2011 May 2. Arch Gen Psychiatry. 2011. PMID: 21536970 Free PMC article.
270 results