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Combined ART started during acute HIV infection protects central memory CD4+ T cells and can induce remission.
Chéret A, Bacchus-Souffan C, Avettand-Fenoël V, Mélard A, Nembot G, Blanc C, Samri A, Sáez-Cirión A, Hocqueloux L, Lascoux-Combe C, Allavena C, Goujard C, Valantin MA, Leplatois A, Meyer L, Rouzioux C, Autran B; OPTIPRIM ANRS-147 Study Group. Chéret A, et al. J Antimicrob Chemother. 2015 Jul;70(7):2108-20. doi: 10.1093/jac/dkv084. Epub 2015 Apr 21. J Antimicrob Chemother. 2015. PMID: 25900157 Clinical Trial.
HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype.
Sáez-Cirión A, Lacabaratz C, Lambotte O, Versmisse P, Urrutia A, Boufassa F, Barré-Sinoussi F, Delfraissy JF, Sinet M, Pancino G, Venet A; Agence Nationale de Recherches sur le Sida EP36 HIV Controllers Study Group. Sáez-Cirión A, et al. Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6776-81. doi: 10.1073/pnas.0611244104. Epub 2007 Apr 11. Proc Natl Acad Sci U S A. 2007. PMID: 17428922 Free PMC article.
Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: association with Gag-specific CD8 T cell responses.
Sáez-Cirión A, Sinet M, Shin SY, Urrutia A, Versmisse P, Lacabaratz C, Boufassa F, Avettand-Fènoël V, Rouzioux C, Delfraissy JF, Barré-Sinoussi F, Lambotte O, Venet A, Pancino G; ANRS EP36 HIV Controllers Study Group. Sáez-Cirión A, et al. J Immunol. 2009 Jun 15;182(12):7828-37. doi: 10.4049/jimmunol.0803928. J Immunol. 2009. PMID: 19494307
Restriction of HIV-1 replication in macrophages and CD4+ T cells from HIV controllers.
Sáez-Cirión A, Hamimi C, Bergamaschi A, David A, Versmisse P, Mélard A, Boufassa F, Barré-Sinoussi F, Lambotte O, Rouzioux C, Pancino G; ANRS CO18 Cohort. Sáez-Cirión A, et al. Blood. 2011 Jul 28;118(4):955-64. doi: 10.1182/blood-2010-12-327106. Epub 2011 Jun 3. Blood. 2011. PMID: 21642597 Free PMC article.
117 results