Neidle S - Search Results

1

Macrocyclic naphthalene diimides as G-quadruplex binders.

Marchetti C, Minarini A, Tumiatti V, Moraca F, Parrotta L, Alcaro S, Rigo R, Sissi C, Gunaratnam M, Ohnmacht SA, Neidle S, Milelli A. Marchetti C, et al. Among authors: neidle s. Bioorg Med Chem. 2015 Jul 1;23(13):3819-30. doi: 10.1016/j.bmc.2015.03.076. Epub 2015 Apr 11. Bioorg Med Chem. 2015. PMID: 25935290

2

Human telomerase inhibition by substituted acridine derivatives.

Harrison RJ, Gowan SM, Kelland LR, Neidle S. Harrison RJ, et al. Among authors: neidle s. Bioorg Med Chem Lett. 1999 Sep 6;9(17):2463-8. doi: 10.1016/s0960-894x(99)00394-7. Bioorg Med Chem Lett. 1999. PMID: 10498189

3

Molecular modeling studies on G-quadruplex complexes of telomerase inhibitors: structure-activity relationships.

Read MA, Wood AA, Harrison JR, Gowan SM, Kelland LR, Dosanjh HS, Neidle S. Read MA, et al. Among authors: neidle s. J Med Chem. 1999 Nov 4;42(22):4538-46. doi: 10.1021/jm990287e. J Med Chem. 1999. PMID: 10579817

4

DNA minor groove interactions and the biological activity of 2,5-bis.

Simpson IJ, Lee M, Kumar A, Boykin DW, Neidle S. Simpson IJ, et al. Among authors: neidle s. Bioorg Med Chem Lett. 2000 Dec 4;10(23):2593-7. doi: 10.1016/s0960-894x(00)00511-4. Bioorg Med Chem Lett. 2000. PMID: 11128631

5

Trisubstituted acridine derivatives as potent and selective telomerase inhibitors.

Harrison RJ, Cuesta J, Chessari G, Read MA, Basra SK, Reszka AP, Morrell J, Gowan SM, Incles CM, Tanious FA, Wilson WD, Kelland LR, Neidle S. Harrison RJ, et al. Among authors: neidle s. J Med Chem. 2003 Oct 9;46(21):4463-76. doi: 10.1021/jm0308693. J Med Chem. 2003. PMID: 14521409

6

Synthesis, biophysical and biological evaluation of 3,6-bis-amidoacridines with extended 9-anilino substituents as potent G-quadruplex-binding telomerase inhibitors.

Schultes CM, Guyen B, Cuesta J, Neidle S. Schultes CM, et al. Among authors: neidle s. Bioorg Med Chem Lett. 2004 Aug 16;14(16):4347-51. doi: 10.1016/j.bmcl.2004.05.090. Bioorg Med Chem Lett. 2004. PMID: 15261300

7

Evaluation of by disubstituted acridone derivatives as telomerase inhibitors: the importance of G-quadruplex binding.

Harrison RJ, Reszka AP, Haider SM, Romagnoli B, Morrell J, Read MA, Gowan SM, Incles CM, Kelland LR, Neidle S. Harrison RJ, et al. Among authors: neidle s. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5845-9. doi: 10.1016/j.bmcl.2004.09.037. Bioorg Med Chem Lett. 2004. PMID: 15501053

8

Truncated azinomycin analogues intercalate into DNA.

Casely-Hayford MA, Pors K, Patterson LH, Gerner C, Neidle S, Searcey M. Casely-Hayford MA, et al. Among authors: neidle s. Bioorg Med Chem Lett. 2005 Feb 1;15(3):653-6. doi: 10.1016/j.bmcl.2004.11.037. Bioorg Med Chem Lett. 2005. PMID: 15664831

9

Targeting the DNA minor groove with fused ring dicationic compounds: comparison of in silico screening and a high-resolution crystal structure.

Campbell NH, Evans DA, Lee MP, Parkinson GN, Neidle S. Campbell NH, et al. Among authors: neidle s. Bioorg Med Chem Lett. 2006 Jan 1;16(1):15-9. doi: 10.1016/j.bmcl.2005.10.036. Epub 2005 Nov 2. Bioorg Med Chem Lett. 2006. PMID: 16263285

10

Natural and synthetic G-quadruplex interactive berberine derivatives.

Franceschin M, Rossetti L, D'Ambrosio A, Schirripa S, Bianco A, Ortaggi G, Savino M, Schultes C, Neidle S. Franceschin M, et al. Among authors: neidle s. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1707-11. doi: 10.1016/j.bmcl.2005.12.001. Epub 2006 Jan 11. Bioorg Med Chem Lett. 2006. PMID: 16377184

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