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Page 1
Macrocyclic naphthalene diimides as G-quadruplex binders.
Marchetti C, Minarini A, Tumiatti V, Moraca F, Parrotta L, Alcaro S, Rigo R, Sissi C, Gunaratnam M, Ohnmacht SA, Neidle S, Milelli A. Marchetti C, et al. Among authors: ohnmacht sa. Bioorg Med Chem. 2015 Jul 1;23(13):3819-30. doi: 10.1016/j.bmc.2015.03.076. Epub 2015 Apr 11. Bioorg Med Chem. 2015. PMID: 25935290
Small-molecule quadruplex-targeted drug discovery.
Ohnmacht SA, Neidle S. Ohnmacht SA, et al. Bioorg Med Chem Lett. 2014 Jun 15;24(12):2602-12. doi: 10.1016/j.bmcl.2014.04.029. Epub 2014 Apr 18. Bioorg Med Chem Lett. 2014. PMID: 24814531
Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G-Quadruplex-Binding Small Molecule.
Marchetti C, Zyner KG, Ohnmacht SA, Robson M, Haider SM, Morton JP, Marsico G, Vo T, Laughlin-Toth S, Ahmed AA, Di Vita G, Pazitna I, Gunaratnam M, Besser RJ, Andrade ACG, Diocou S, Pike JA, Tannahill D, Pedley RB, Evans TRJ, Wilson WD, Balasubramanian S, Neidle S. Marchetti C, et al. Among authors: ohnmacht sa. J Med Chem. 2018 Mar 22;61(6):2500-2517. doi: 10.1021/acs.jmedchem.7b01781. Epub 2018 Feb 7. J Med Chem. 2018. PMID: 29356532 Free PMC article.
Discovery of new G-quadruplex binding chemotypes.
Ohnmacht SA, Varavipour E, Nanjunda R, Pazitna I, Di Vita G, Gunaratnam M, Kumar A, Ismail MA, Boykin DW, Wilson WD, Neidle S. Ohnmacht SA, et al. Chem Commun (Camb). 2014 Jan 28;50(8):960-3. doi: 10.1039/c3cc48616h. Chem Commun (Camb). 2014. PMID: 24302123 Free PMC article.
24 results