Ding J - Search Results

1

Negative feedback-defective PRPS1 mutants drive thiopurine resistance in relapsed childhood ALL.

Li B, Li H, Bai Y, Kirschner-Schwabe R, Yang JJ, Chen Y, Lu G, Tzoneva G, Ma X, Wu T, Li W, Lu H, Ding L, Liang H, Huang X, Yang M, Jin L, Kang H, Chen S, Du A, Shen S, Ding J, Chen H, Chen J, von Stackelberg A, Gu L, Zhang J, Ferrando A, Tang J, Wang S, Zhou BB. Li B, et al. Among authors: ding l, ding j. Nat Med. 2015 Jun;21(6):563-71. doi: 10.1038/nm.3840. Epub 2015 May 11. Nat Med. 2015. PMID: 25962120 Free PMC article.

2

The catalytic intermediate stabilized by a "down" active site loop for diaminopimelate decarboxylase from Helicobacter pylori. Enzymatic characterization with crystal structure analysis.

Hu T, Wu D, Chen J, Ding J, Jiang H, Shen X. Hu T, et al. Among authors: ding j. J Biol Chem. 2008 Jul 25;283(30):21284-93. doi: 10.1074/jbc.M801823200. Epub 2008 May 28. J Biol Chem. 2008. PMID: 18508763 Free PMC article.

3

Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.

Xu S, Li W, Zhu J, Wang R, Li Z, Xu GL, Ding J. Xu S, et al. Among authors: ding j. Cell Res. 2013 Nov;23(11):1296-309. doi: 10.1038/cr.2013.107. Epub 2013 Aug 6. Cell Res. 2013. PMID: 23917530 Free PMC article.

4

Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi.

Li W, Zhang T, Ding J. Li W, et al. Among authors: ding j. Nucleic Acids Res. 2015 Nov 16;43(20):10026-38. doi: 10.1093/nar/gkv979. Epub 2015 Oct 1. Nucleic Acids Res. 2015. PMID: 26429971 Free PMC article.

5

Insights into the inhibitory mechanisms of NADH on the αγ heterodimer of human NAD-dependent isocitrate dehydrogenase.

Liu Y, Hu L, Ma T, Yang J, Ding J. Liu Y, et al. Among authors: ding j. Sci Rep. 2018 Feb 16;8(1):3146. doi: 10.1038/s41598-018-21584-7. Sci Rep. 2018. PMID: 29453450 Free PMC article.

6

Structural insights into the activation of USP46 by WDR48 and WDR20.

Zhu H, Zhang T, Wang F, Yang J, Ding J. Zhu H, et al. Among authors: ding j. Cell Discov. 2019 Jul 2;5:34. doi: 10.1038/s41421-019-0102-1. eCollection 2019. Cell Discov. 2019. PMID: 31632687 Free PMC article. No abstract available.

7

Structural insight into human N6amt1-Trm112 complex functioning as a protein methyltransferase.

Li W, Shi Y, Zhang T, Ye J, Ding J. Li W, et al. Among authors: ding j. Cell Discov. 2019 Sep 10;5:51. doi: 10.1038/s41421-019-0121-y. eCollection 2019. Cell Discov. 2019. PMID: 31636962 Free PMC article.

8

Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations.

Yang J, Zhu H, Zhang T, Ding J. Yang J, et al. Among authors: ding j. Cell Discov. 2021 Jan 12;7(1):3. doi: 10.1038/s41421-020-00227-0. Cell Discov. 2021. PMID: 33431826 Free PMC article.

9

Molecular mechanism for vitamin C-derived C⁵-glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1.

Li W, Zhang T, Sun M, Shi Y, Zhang XJ, Xu GL, Ding J. Li W, et al. Among authors: ding j. Nat Commun. 2021 Feb 2;12(1):744. doi: 10.1038/s41467-021-21061-2. Nat Commun. 2021. PMID: 33531488 Free PMC article.

10

Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.

Jin S, Chen X, Yang J, Ding J. Jin S, et al. Among authors: ding j. Nat Commun. 2023 Oct 20;14(1):6638. doi: 10.1038/s41467-023-42456-3. Nat Commun. 2023. PMID: 37863926 Free PMC article.

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