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Bile acids induce pancreatic acinar cell injury and pancreatitis by activating calcineurin.
Muili KA, Wang D, Orabi AI, Sarwar S, Luo Y, Javed TA, Eisses JF, Mahmood SM, Jin S, Singh VP, Ananthanaravanan M, Perides G, Williams JA, Molkentin JD, Husain SZ. Muili KA, et al. Among authors: jin s. J Biol Chem. 2013 Jan 4;288(1):570-80. doi: 10.1074/jbc.M112.428896. Epub 2012 Nov 12. J Biol Chem. 2013. PMID: 23148215 Free PMC article.
The ryanodine receptor is expressed in human pancreatic acinar cells and contributes to acinar cell injury.
Lewarchik CM, Orabi AI, Jin S, Wang D, Muili KA, Shah AU, Eisses JF, Malik A, Bottino R, Jayaraman T, Husain SZ. Lewarchik CM, et al. Among authors: jin s. Am J Physiol Gastrointest Liver Physiol. 2014 Sep 1;307(5):G574-81. doi: 10.1152/ajpgi.00143.2014. Epub 2014 Jul 10. Am J Physiol Gastrointest Liver Physiol. 2014. PMID: 25012845 Free PMC article.
Valproic Acid Limits Pancreatic Recovery after Pancreatitis by Inhibiting Histone Deacetylases and Preventing Acinar Redifferentiation Programs.
Eisses JF, Criscimanna A, Dionise ZR, Orabi AI, Javed TA, Sarwar S, Jin S, Zhou L, Singh S, Poddar M, Davis AW, Tosun AB, Ozolek JA, Lowe ME, Monga SP, Rohde GK, Esni F, Husain SZ. Eisses JF, et al. Among authors: jin s. Am J Pathol. 2015 Dec;185(12):3304-15. doi: 10.1016/j.ajpath.2015.08.006. Epub 2015 Oct 23. Am J Pathol. 2015. PMID: 26476347 Free PMC article.
Gfi1 expressed in bone marrow stromal cells is a novel osteoblast suppressor in patients with multiple myeloma bone disease.
D'Souza S, del Prete D, Jin S, Sun Q, Huston AJ, Kostov FE, Sammut B, Hong CS, Anderson JL, Patrene KD, Yu S, Velu CS, Xiao G, Grimes HL, Roodman GD, Galson DL. D'Souza S, et al. Among authors: jin s. Blood. 2011 Dec 22;118(26):6871-80. doi: 10.1182/blood-2011-04-346775. Epub 2011 Oct 31. Blood. 2011. PMID: 22042697 Free PMC article.
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