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Page 1
Macrophage Mitochondrial Energy Status Regulates Cholesterol Efflux and Is Enhanced by Anti-miR33 in Atherosclerosis.
Karunakaran D, Thrush AB, Nguyen MA, Richards L, Geoffrion M, Singaravelu R, Ramphos E, Shangari P, Ouimet M, Pezacki JP, Moore KJ, Perisic L, Maegdefessel L, Hedin U, Harper ME, Rayner KJ. Karunakaran D, et al. Among authors: geoffrion m. Circ Res. 2015 Jul 17;117(3):266-78. doi: 10.1161/CIRCRESAHA.117.305624. Epub 2015 May 22. Circ Res. 2015. PMID: 26002865 Free PMC article.
Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.
Ramkhelawon B, Hennessy EJ, Ménager M, Ray TD, Sheedy FJ, Hutchison S, Wanschel A, Oldebeken S, Geoffrion M, Spiro W, Miller G, McPherson R, Rayner KJ, Moore KJ. Ramkhelawon B, et al. Among authors: geoffrion m. Nat Med. 2014 Apr;20(4):377-84. doi: 10.1038/nm.3467. Epub 2014 Mar 2. Nat Med. 2014. PMID: 24584118 Free PMC article.
IRF2BP2 Reduces Macrophage Inflammation and Susceptibility to Atherosclerosis.
Chen HH, Keyhanian K, Zhou X, Vilmundarson RO, Almontashiri NA, Cruz SA, Pandey NR, Lerma Yap N, Ho T, Stewart CA, Huang H, Hari A, Geoffrion M, McPherson R, Rayner KJ, Stewart AF. Chen HH, et al. Among authors: geoffrion m. Circ Res. 2015 Sep 25;117(8):671-83. doi: 10.1161/CIRCRESAHA.114.305777. Epub 2015 Jul 20. Circ Res. 2015. PMID: 26195219
Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis.
Karunakaran D, Geoffrion M, Wei L, Gan W, Richards L, Shangari P, DeKemp EM, Beanlands RA, Perisic L, Maegdefessel L, Hedin U, Sad S, Guo L, Kolodgie FD, Virmani R, Ruddy T, Rayner KJ. Karunakaran D, et al. Among authors: geoffrion m. Sci Adv. 2016 Jul 22;2(7):e1600224. doi: 10.1126/sciadv.1600224. eCollection 2016 Jul. Sci Adv. 2016. PMID: 27532042 Free PMC article.
Paradoxical Suppression of Atherosclerosis in the Absence of microRNA-146a.
Cheng HS, Besla R, Li A, Chen Z, Shikatani EA, Nazari-Jahantigh M, Hammoutène A, Nguyen MA, Geoffrion M, Cai L, Khyzha N, Li T, MacParland SA, Husain M, Cybulsky MI, Boulanger CM, Temel RE, Schober A, Rayner KJ, Robbins CS, Fish JE. Cheng HS, et al. Among authors: geoffrion m. Circ Res. 2017 Aug 4;121(4):354-367. doi: 10.1161/CIRCRESAHA.116.310529. Epub 2017 Jun 21. Circ Res. 2017. PMID: 28637783 Free PMC article.
Loss of MLKL (Mixed Lineage Kinase Domain-Like Protein) Decreases Necrotic Core but Increases Macrophage Lipid Accumulation in Atherosclerosis.
Rasheed A, Robichaud S, Nguyen MA, Geoffrion M, Wyatt H, Cottee ML, Dennison T, Pietrangelo A, Lee R, Lagace TA, Ouimet M, Rayner KJ. Rasheed A, et al. Among authors: geoffrion m. Arterioscler Thromb Vasc Biol. 2020 May;40(5):1155-1167. doi: 10.1161/ATVBAHA.119.313640. Epub 2020 Mar 26. Arterioscler Thromb Vasc Biol. 2020. PMID: 32212851 Free article.
RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice.
Karunakaran D, Turner AW, Duchez AC, Soubeyrand S, Rasheed A, Smyth D, Cook DP, Nikpay M, Kandiah JW, Pan C, Geoffrion M, Lee R, Boytard L, Wyatt H, Nguyen MA, Lau P, Laakso M, Ramkhelawon B, Alvarez M, Pietiläinen KH, Pajukanta P, Vanderhyden BC, Liu P, Berger SB, Gough PJ, Bertin J, Harper ME, Lusis AJ, McPherson R, Rayner KJ. Karunakaran D, et al. Among authors: geoffrion m. Nat Metab. 2020 Oct;2(10):1113-1125. doi: 10.1038/s42255-020-00279-2. Epub 2020 Sep 28. Nat Metab. 2020. PMID: 32989316 Free PMC article.
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