Schwabe JWR - Search Results

1

Insights into the Recruitment of Class IIa Histone Deacetylases (HDACs) to the SMRT/NCoR Transcriptional Repression Complex.

Hudson GM, Watson PJ, Fairall L, Jamieson AG, Schwabe JWR. Hudson GM, et al. Among authors: schwabe jwr. J Biol Chem. 2015 Jul 17;290(29):18237-18244. doi: 10.1074/jbc.M115.661058. Epub 2015 Jun 8. J Biol Chem. 2015. PMID: 26055705 Free PMC article.

2

The cocrystal structures of two zinc-stabilized DNA-binding domains illustrate different ways of achieving sequence-specific DNA recognition.

Schwabe JW, Fairall L, Chapman L, Finch JT, Dutnall RN, Rhodes D. Schwabe JW, et al. Cold Spring Harb Symp Quant Biol. 1993;58:141-7. doi: 10.1101/sqb.1993.058.01.018. Cold Spring Harb Symp Quant Biol. 1993. PMID: 7956024 No abstract available.

3

The crystal structure of a two zinc-finger peptide reveals an extension to the rules for zinc-finger/DNA recognition.

Fairall L, Schwabe JW, Chapman L, Finch JT, Rhodes D. Fairall L, et al. Nature. 1993 Dec 2;366(6454):483-7. doi: 10.1038/366483a0. Nature. 1993. PMID: 8247159

4

Towards an understanding of protein-DNA recognition.

Rhodes D, Schwabe JW, Chapman L, Fairall L. Rhodes D, et al. Philos Trans R Soc Lond B Biol Sci. 1996 Apr 29;351(1339):501-9. doi: 10.1098/rstb.1996.0048. Philos Trans R Soc Lond B Biol Sci. 1996. PMID: 8735272 Review.

5

A dominant-negative peroxisome proliferator-activated receptor gamma (PPARgamma) mutant is a constitutive repressor and inhibits PPARgamma-mediated adipogenesis.

Gurnell M, Wentworth JM, Agostini M, Adams M, Collingwood TN, Provenzano C, Browne PO, Rajanayagam O, Burris TP, Schwabe JW, Lazar MA, Chatterjee VK. Gurnell M, et al. J Biol Chem. 2000 Feb 25;275(8):5754-9. doi: 10.1074/jbc.275.8.5754. J Biol Chem. 2000. PMID: 10681562 Free article.

6

Molecular determinants of the balance between co-repressor and co-activator recruitment to the retinoic acid receptor.

Benko S, Love JD, Beládi M, Schwabe JW, Nagy L. Benko S, et al. J Biol Chem. 2003 Oct 31;278(44):43797-806. doi: 10.1074/jbc.M306199200. Epub 2003 Aug 12. J Biol Chem. 2003. PMID: 12917445 Free article.

7

Identification of a novel co-regulator interaction surface on the ligand binding domain of Nurr1 using NMR footprinting.

Codina A, Benoit G, Gooch JT, Neuhaus D, Perlmann T, Schwabe JW. Codina A, et al. J Biol Chem. 2004 Dec 17;279(51):53338-45. doi: 10.1074/jbc.M409096200. Epub 2004 Sep 28. J Biol Chem. 2004. PMID: 15456745 Free article.

8

Structural basis for the activation of PPARgamma by oxidized fatty acids.

Itoh T, Fairall L, Amin K, Inaba Y, Szanto A, Balint BL, Nagy L, Yamamoto K, Schwabe JW. Itoh T, et al. Nat Struct Mol Biol. 2008 Sep;15(9):924-31. doi: 10.1038/nsmb.1474. Nat Struct Mol Biol. 2008. PMID: 19172745 Free PMC article.

9

Negative regulation by nuclear receptors: a plethora of mechanisms.

Santos GM, Fairall L, Schwabe JW. Santos GM, et al. Trends Endocrinol Metab. 2011 Mar;22(3):87-93. doi: 10.1016/j.tem.2010.11.004. Epub 2010 Dec 31. Trends Endocrinol Metab. 2011. PMID: 21196123 Free PMC article. Review.

10

Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery.

Oberoi J, Fairall L, Watson PJ, Yang JC, Czimmerer Z, Kampmann T, Goult BT, Greenwood JA, Gooch JT, Kallenberger BC, Nagy L, Neuhaus D, Schwabe JW. Oberoi J, et al. Nat Struct Mol Biol. 2011 Feb;18(2):177-84. doi: 10.1038/nsmb.1983. Epub 2011 Jan 16. Nat Struct Mol Biol. 2011. PMID: 21240272 Free PMC article.

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