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Dexmedetomidine increases tau phosphorylation under normothermic conditions in vivo and in vitro.
Whittington RA, Virág L, Gratuze M, Petry FR, Noël A, Poitras I, Truchetti G, Marcouiller F, Papon MA, El Khoury N, Wong K, Bretteville A, Morin F, Planel E. Whittington RA, et al. Among authors: marcouiller f. Neurobiol Aging. 2015 Aug;36(8):2414-28. doi: 10.1016/j.neurobiolaging.2015.05.002. Epub 2015 May 9. Neurobiol Aging. 2015. PMID: 26058840 Free PMC article.
Propofol directly increases tau phosphorylation.
Whittington RA, Virág L, Marcouiller F, Papon MA, El Khoury NB, Julien C, Morin F, Emala CW, Planel E. Whittington RA, et al. Among authors: marcouiller f. PLoS One. 2011 Jan 31;6(1):e16648. doi: 10.1371/journal.pone.0016648. PLoS One. 2011. PMID: 21304998 Free PMC article.
Hypothermia mediates age-dependent increase of tau phosphorylation in db/db mice.
El Khoury NB, Gratuze M, Petry F, Papon MA, Julien C, Marcouiller F, Morin F, Nicholls SB, Calon F, Hébert SS, Marette A, Planel E. El Khoury NB, et al. Among authors: marcouiller f. Neurobiol Dis. 2016 Apr;88:55-65. doi: 10.1016/j.nbd.2016.01.005. Epub 2016 Jan 9. Neurobiol Dis. 2016. PMID: 26777665
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