Timchalk C - Search Results

1

Computational strategy for quantifying human pesticide exposure based upon a saliva measurement.

Timchalk C, Weber TJ, Smith JN. Timchalk C, et al. Front Pharmacol. 2015 May 27;6:115. doi: 10.3389/fphar.2015.00115. eCollection 2015. Front Pharmacol. 2015. PMID: 26074822 Free PMC article. Review.

2

Non-invasive saliva human biomonitoring: development of an in vitro platform.

Weber TJ, Smith JN, Carver ZA, Timchalk C. Weber TJ, et al. Among authors: timchalk c. J Expo Sci Environ Epidemiol. 2017 Jan;27(1):72-77. doi: 10.1038/jes.2015.74. Epub 2015 Nov 11. J Expo Sci Environ Epidemiol. 2017. PMID: 26555474

3

Predicting Transport of 3,5,6-Trichloro-2-Pyridinol Into Saliva Using a Combination Experimental and Computational Approach.

Smith JN, Carver ZA, Weber TJ, Timchalk C. Smith JN, et al. Among authors: timchalk c. Toxicol Sci. 2017 Jun 1;157(2):438-450. doi: 10.1093/toxsci/kfx055. Toxicol Sci. 2017. PMID: 28402492

4

A multi-route model of nicotine-cotinine pharmacokinetics, pharmacodynamics and brain nicotinic acetylcholine receptor binding in humans.

Teeguarden JG, Housand CJ, Smith JN, Hinderliter PM, Gunawan R, Timchalk CA. Teeguarden JG, et al. Regul Toxicol Pharmacol. 2013 Feb;65(1):12-28. doi: 10.1016/j.yrtph.2012.10.007. Epub 2012 Oct 23. Regul Toxicol Pharmacol. 2013. PMID: 23099439

5

Pharmacokinetics of the chlorpyrifos metabolite 3,5,6-trichloro-2-pyridinol (TCPy) in rat saliva.

Smith JN, Wang J, Lin Y, Timchalk C. Smith JN, et al. Among authors: timchalk c. Toxicol Sci. 2010 Feb;113(2):315-25. doi: 10.1093/toxsci/kfp283. Epub 2009 Nov 17. Toxicol Sci. 2010. PMID: 19920072

6

Effect of in vivo nicotine exposure on chlorpyrifos pharmacokinetics and pharmacodynamics in rats.

Lee S, Poet TS, Smith JN, Busby-Hjerpe AL, Timchalk C. Lee S, et al. Among authors: timchalk c. Chem Biol Interact. 2010 Mar 30;184(3):449-57. doi: 10.1016/j.cbi.2010.01.024. Epub 2010 Jan 25. Chem Biol Interact. 2010. PMID: 20097188

7

Magnetic electrochemical sensing platform for biomonitoring of exposure to organophosphorus pesticides and nerve agents based on simultaneous measurement of total enzyme amount and enzyme activity.

Du D, Wang J, Wang L, Lu D, Smith JN, Timchalk C, Lin Y. Du D, et al. Among authors: timchalk c. Anal Chem. 2011 May 15;83(10):3770-7. doi: 10.1021/ac200217d. Epub 2011 Apr 21. Anal Chem. 2011. PMID: 21462919

8

Pharmacokinetics and pharmacodynamics of chlorpyrifos and 3,5,6-trichloro-2-pyridinol in rat saliva after chlorpyrifos administration.

Smith JN, Wang J, Lin Y, Klohe EM, Timchalk C. Smith JN, et al. Among authors: timchalk c. Toxicol Sci. 2012 Dec;130(2):245-56. doi: 10.1093/toxsci/kfs251. Epub 2012 Aug 8. Toxicol Sci. 2012. PMID: 22874420

9

A human life-stage physiologically based pharmacokinetic and pharmacodynamic model for chlorpyrifos: development and validation.

Smith JN, Hinderliter PM, Timchalk C, Bartels MJ, Poet TS. Smith JN, et al. Among authors: timchalk c. Regul Toxicol Pharmacol. 2014 Aug;69(3):580-97. doi: 10.1016/j.yrtph.2013.10.005. Epub 2013 Nov 4. Regul Toxicol Pharmacol. 2014. PMID: 24200834

10

Use of a probabilistic PBPK/PD model to calculate Data Derived Extrapolation Factors for chlorpyrifos.

Poet TS, Timchalk C, Bartels MJ, Smith JN, McDougal R, Juberg DR, Price PS. Poet TS, et al. Among authors: timchalk c. Regul Toxicol Pharmacol. 2017 Jun;86:59-73. doi: 10.1016/j.yrtph.2017.02.014. Epub 2017 Feb 24. Regul Toxicol Pharmacol. 2017. PMID: 28238854

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