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Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes.
Xue R, Lynes MD, Dreyfuss JM, Shamsi F, Schulz TJ, Zhang H, Huang TL, Townsend KL, Li Y, Takahashi H, Weiner LS, White AP, Lynes MS, Rubin LL, Goodyear LJ, Cypess AM, Tseng YH. Xue R, et al. Among authors: goodyear lj. Nat Med. 2015 Jul;21(7):760-8. doi: 10.1038/nm.3881. Epub 2015 Jun 15. Nat Med. 2015. PMID: 26076036 Free PMC article.
Brown adipose tissue regulates glucose homeostasis and insulin sensitivity.
Stanford KI, Middelbeek RJ, Townsend KL, An D, Nygaard EB, Hitchcox KM, Markan KR, Nakano K, Hirshman MF, Tseng YH, Goodyear LJ. Stanford KI, et al. Among authors: goodyear lj. J Clin Invest. 2013 Jan;123(1):215-23. doi: 10.1172/JCI62308. Epub 2012 Dec 10. J Clin Invest. 2013. PMID: 23221344 Free PMC article.
Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance.
Liew CW, Boucher J, Cheong JK, Vernochet C, Koh HJ, Mallol C, Townsend K, Langin D, Kawamori D, Hu J, Tseng YH, Hellerstein MK, Farmer SR, Goodyear L, Doria A, Blüher M, Hsu SI, Kulkarni RN. Liew CW, et al. Nat Med. 2013 Feb;19(2):217-26. doi: 10.1038/nm.3056. Epub 2013 Jan 6. Nat Med. 2013. PMID: 23291629 Free PMC article.
MicroRNA-455 regulates brown adipogenesis via a novel HIF1an-AMPK-PGC1α signaling network.
Zhang H, Guan M, Townsend KL, Huang TL, An D, Yan X, Xue R, Schulz TJ, Winnay J, Mori M, Hirshman MF, Kristiansen K, Tsang JS, White AP, Cypess AM, Goodyear LJ, Tseng YH. Zhang H, et al. Among authors: goodyear lj. EMBO Rep. 2015 Oct;16(10):1378-93. doi: 10.15252/embr.201540837. Epub 2015 Aug 24. EMBO Rep. 2015. PMID: 26303948 Free PMC article.
Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism.
Lerin C, Goldfine AB, Boes T, Liu M, Kasif S, Dreyfuss JM, De Sousa-Coelho AL, Daher G, Manoli I, Sysol JR, Isganaitis E, Jessen N, Goodyear LJ, Beebe K, Gall W, Venditti CP, Patti ME. Lerin C, et al. Among authors: goodyear lj. Mol Metab. 2016 Aug 6;5(10):926-936. doi: 10.1016/j.molmet.2016.08.001. eCollection 2016 Oct. Mol Metab. 2016. PMID: 27689005 Free PMC article.
238 results