Gocheva V - Search Results

1

Proteomic Identification of Cysteine Cathepsin Substrates Shed from the Surface of Cancer Cells.

Sobotič B, Vizovišek M, Vidmar R, Van Damme P, Gocheva V, Joyce JA, Gevaert K, Turk V, Turk B, Fonović M. Sobotič B, et al. Among authors: gocheva v. Mol Cell Proteomics. 2015 Aug;14(8):2213-28. doi: 10.1074/mcp.M114.044628. Epub 2015 Jun 16. Mol Cell Proteomics. 2015. PMID: 26081835 Free PMC article.

2

Cysteine cathepsins and the cutting edge of cancer invasion.

Gocheva V, Joyce JA. Gocheva V, et al. Cell Cycle. 2007 Jan 1;6(1):60-4. doi: 10.4161/cc.6.1.3669. Epub 2007 Jan 6. Cell Cycle. 2007. PMID: 17245112 Review.

3

Distinct roles for cysteine cathepsin genes in multistage tumorigenesis.

Gocheva V, Zeng W, Ke D, Klimstra D, Reinheckel T, Peters C, Hanahan D, Joyce JA. Gocheva V, et al. Genes Dev. 2006 Mar 1;20(5):543-56. doi: 10.1101/gad.1407406. Epub 2006 Feb 15. Genes Dev. 2006. PMID: 16481467 Free PMC article.

4

IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion.

Gocheva V, Wang HW, Gadea BB, Shree T, Hunter KE, Garfall AL, Berman T, Joyce JA. Gocheva V, et al. Genes Dev. 2010 Feb 1;24(3):241-55. doi: 10.1101/gad.1874010. Epub 2010 Jan 15. Genes Dev. 2010. PMID: 20080943 Free PMC article.

5

Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model.

Elie BT, Gocheva V, Shree T, Dalrymple SA, Holsinger LJ, Joyce JA. Elie BT, et al. Among authors: gocheva v. Biochimie. 2010 Nov;92(11):1618-24. doi: 10.1016/j.biochi.2010.04.023. Epub 2010 May 4. Biochimie. 2010. PMID: 20447439 Free PMC article.

6

Deletion of cathepsin H perturbs angiogenic switching, vascularization and growth of tumors in a mouse model of pancreatic islet cell cancer.

Gocheva V, Chen X, Peters C, Reinheckel T, Joyce JA. Gocheva V, et al. Biol Chem. 2010 Aug;391(8):937-45. doi: 10.1515/BC.2010.080. Biol Chem. 2010. PMID: 20731543 Free PMC article.

7

Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix.

Akkari L, Gocheva V, Kester JC, Hunter KE, Quick ML, Sevenich L, Wang HW, Peters C, Tang LH, Klimstra DS, Reinheckel T, Joyce JA. Akkari L, et al. Among authors: gocheva v. Genes Dev. 2014 Oct 1;28(19):2134-50. doi: 10.1101/gad.249599.114. Genes Dev. 2014. PMID: 25274726 Free PMC article.

8

Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer.

Akkari L, Gocheva V, Quick ML, Kester JC, Spencer AK, Garfall AL, Bowman RL, Joyce JA. Akkari L, et al. Among authors: gocheva v. Genes Dev. 2016 Jan 15;30(2):220-32. doi: 10.1101/gad.270439.115. Genes Dev. 2016. PMID: 26773004 Free PMC article.

9

TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors.

Prudova A, Gocheva V, Auf dem Keller U, Eckhard U, Olson OC, Akkari L, Butler GS, Fortelny N, Lange PF, Mark JC, Joyce JA, Overall CM. Prudova A, et al. Among authors: gocheva v. Cell Rep. 2016 Aug 9;16(6):1762-1773. doi: 10.1016/j.celrep.2016.06.086. Epub 2016 Jul 28. Cell Rep. 2016. PMID: 27477282 Free article.

10

Deficiency of the macrophage growth factor CSF-1 disrupts pancreatic neuroendocrine tumor development.

Pyonteck SM, Gadea BB, Wang HW, Gocheva V, Hunter KE, Tang LH, Joyce JA. Pyonteck SM, et al. Among authors: gocheva v. Oncogene. 2012 Mar 15;31(11):1459-67. doi: 10.1038/onc.2011.337. Epub 2011 Aug 8. Oncogene. 2012. PMID: 21822305

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