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Page 1
Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties.
Hartmann J, Wagner KV, Gaali S, Kirschner A, Kozany C, Rühter G, Dedic N, Häusl AS, Hoeijmakers L, Westerholz S, Namendorf C, Gerlach T, Uhr M, Chen A, Deussing JM, Holsboer F, Hausch F, Schmidt MV. Hartmann J, et al. Among authors: holsboer f. J Neurosci. 2015 Jun 17;35(24):9007-16. doi: 10.1523/JNEUROSCI.4024-14.2015. J Neurosci. 2015. PMID: 26085626 Free PMC article.
Individual stress vulnerability is predicted by short-term memory and AMPA receptor subunit ratio in the hippocampus.
Schmidt MV, Trümbach D, Weber P, Wagner K, Scharf SH, Liebl C, Datson N, Namendorf C, Gerlach T, Kühne C, Uhr M, Deussing JM, Wurst W, Binder EB, Holsboer F, Müller MB. Schmidt MV, et al. Among authors: holsboer f. J Neurosci. 2010 Dec 15;30(50):16949-58. doi: 10.1523/JNEUROSCI.4668-10.2010. J Neurosci. 2010. PMID: 21159965 Free PMC article.
The prospect of FKBP51 as a drug target.
Schmidt MV, Paez-Pereda M, Holsboer F, Hausch F. Schmidt MV, et al. Among authors: holsboer f. ChemMedChem. 2012 Aug;7(8):1351-9. doi: 10.1002/cmdc.201200137. Epub 2012 May 13. ChemMedChem. 2012. PMID: 22581765
Differences in FKBP51 regulation following chronic social defeat stress correlate with individual stress sensitivity: influence of paroxetine treatment.
Wagner KV, Marinescu D, Hartmann J, Wang XD, Labermaier C, Scharf SH, Liebl C, Uhr M, Holsboer F, Müller MB, Schmidt MV. Wagner KV, et al. Among authors: holsboer f. Neuropsychopharmacology. 2012 Dec;37(13):2797-808. doi: 10.1038/npp.2012.150. Epub 2012 Aug 8. Neuropsychopharmacology. 2012. PMID: 22871917 Free PMC article.
Homer1 mediates acute stress-induced cognitive deficits in the dorsal hippocampus.
Wagner KV, Hartmann J, Mangold K, Wang XD, Labermaier C, Liebl C, Wolf M, Gassen NC, Holsboer F, Rein T, Müller MB, Schmidt MV. Wagner KV, et al. Among authors: holsboer f. J Neurosci. 2013 Feb 27;33(9):3857-64. doi: 10.1523/JNEUROSCI.4333-12.2013. J Neurosci. 2013. PMID: 23447597 Free PMC article.
Association of FKBP51 with priming of autophagy pathways and mediation of antidepressant treatment response: evidence in cells, mice, and humans.
Gassen NC, Hartmann J, Zschocke J, Stepan J, Hafner K, Zellner A, Kirmeier T, Kollmannsberger L, Wagner KV, Dedic N, Balsevich G, Deussing JM, Kloiber S, Lucae S, Holsboer F, Eder M, Uhr M, Ising M, Schmidt MV, Rein T. Gassen NC, et al. Among authors: holsboer f. PLoS Med. 2014 Nov 11;11(11):e1001755. doi: 10.1371/journal.pmed.1001755. eCollection 2014 Nov. PLoS Med. 2014. PMID: 25386878 Free PMC article.
Urocortin 3 modulates social discrimination abilities via corticotropin-releasing hormone receptor type 2.
Deussing JM, Breu J, Kühne C, Kallnik M, Bunck M, Glasl L, Yen YC, Schmidt MV, Zurmühlen R, Vogl AM, Gailus-Durner V, Fuchs H, Hölter SM, Wotjak CT, Landgraf R, de Angelis MH, Holsboer F, Wurst W. Deussing JM, et al. Among authors: holsboer f. J Neurosci. 2010 Jul 7;30(27):9103-16. doi: 10.1523/JNEUROSCI.1049-10.2010. J Neurosci. 2010. PMID: 20610744 Free PMC article.
The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress.
Hartmann J, Wagner KV, Liebl C, Scharf SH, Wang XD, Wolf M, Hausch F, Rein T, Schmidt U, Touma C, Cheung-Flynn J, Cox MB, Smith DF, Holsboer F, Müller MB, Schmidt MV. Hartmann J, et al. Among authors: holsboer f. Neuropharmacology. 2012 Jan;62(1):332-9. doi: 10.1016/j.neuropharm.2011.07.041. Epub 2011 Aug 4. Neuropharmacology. 2012. PMID: 21839098
Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1.
Refojo D, Schweizer M, Kuehne C, Ehrenberg S, Thoeringer C, Vogl AM, Dedic N, Schumacher M, von Wolff G, Avrabos C, Touma C, Engblom D, Schütz G, Nave KA, Eder M, Wotjak CT, Sillaber I, Holsboer F, Wurst W, Deussing JM. Refojo D, et al. Among authors: holsboer f. Science. 2011 Sep 30;333(6051):1903-7. doi: 10.1126/science.1202107. Epub 2011 Sep 1. Science. 2011. PMID: 21885734
832 results