Dubeau L - Search Results

1

A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan.

Brandhorst S, Choi IY, Wei M, Cheng CW, Sedrakyan S, Navarrete G, Dubeau L, Yap LP, Park R, Vinciguerra M, Di Biase S, Mirzaei H, Mirisola MG, Childress P, Ji L, Groshen S, Penna F, Odetti P, Perin L, Conti PS, Ikeno Y, Kennedy BK, Cohen P, Morgan TE, Dorff TB, Longo VD. Brandhorst S, et al. Among authors: dubeau l. Cell Metab. 2015 Jul 7;22(1):86-99. doi: 10.1016/j.cmet.2015.05.012. Epub 2015 Jun 18. Cell Metab. 2015. PMID: 26094889 Free PMC article. Clinical Trial.

2

Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development.

Dong D, Ni M, Li J, Xiong S, Ye W, Virrey JJ, Mao C, Ye R, Wang M, Pen L, Dubeau L, Groshen S, Hofman FM, Lee AS. Dong D, et al. Among authors: dubeau l. Cancer Res. 2008 Jan 15;68(2):498-505. doi: 10.1158/0008-5472.CAN-07-2950. Cancer Res. 2008. PMID: 18199545

3

Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice.

Lee AS, Brandhorst S, Rangel DF, Navarrete G, Cohen P, Longo VD, Chen J, Groshen S, Morgan TE, Dubeau L. Lee AS, et al. Among authors: dubeau l. Sci Rep. 2017 Feb 1;7:40919. doi: 10.1038/srep40919. Sci Rep. 2017. PMID: 28145503 Free PMC article.

4

GRP78 haploinsufficiency suppresses acinar-to-ductal metaplasia, signaling, and mutant Kras-driven pancreatic tumorigenesis in mice.

Shen J, Ha DP, Zhu G, Rangel DF, Kobielak A, Gill PS, Groshen S, Dubeau L, Lee AS. Shen J, et al. Among authors: dubeau l. Proc Natl Acad Sci U S A. 2017 May 16;114(20):E4020-E4029. doi: 10.1073/pnas.1616060114. Epub 2017 May 1. Proc Natl Acad Sci U S A. 2017. PMID: 28461470 Free PMC article.

5

Endoplasmic reticulum chaperone GRP78/BiP is critical for mutant Kras-driven lung tumorigenesis.

Rangel DF, Dubeau L, Park R, Chan P, Ha DP, Pulido MA, Mullen DJ, Vorobyova I, Zhou B, Borok Z, Offringa IA, Lee AS. Rangel DF, et al. Among authors: dubeau l. Oncogene. 2021 May;40(20):3624-3632. doi: 10.1038/s41388-021-01791-9. Epub 2021 Apr 30. Oncogene. 2021. PMID: 33931739 Free PMC article.

6

Genome-scale screen for DNA methylation-based detection markers for ovarian cancer.

Campan M, Moffitt M, Houshdaran S, Shen H, Widschwendter M, Daxenbichler G, Long T, Marth C, Laird-Offringa IA, Press MF, Dubeau L, Siegmund KD, Wu AH, Groshen S, Chandavarkar U, Roman LD, Berchuck A, Pearce CL, Laird PW. Campan M, et al. Among authors: dubeau l. PLoS One. 2011;6(12):e28141. doi: 10.1371/journal.pone.0028141. Epub 2011 Dec 7. PLoS One. 2011. PMID: 22163280 Free PMC article.

7

Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis.

Wang M, Ye R, Barron E, Baumeister P, Mao C, Luo S, Fu Y, Luo B, Dubeau L, Hinton DR, Lee AS. Wang M, et al. Among authors: dubeau l. Cell Death Differ. 2010 Mar;17(3):488-98. doi: 10.1038/cdd.2009.144. Epub 2009 Oct 9. Cell Death Differ. 2010. PMID: 19816510 Free PMC article.

8

A Phosphotyrosine Switch in Estrogen Receptor β Is Required for Mouse Ovarian Function.

Yuan B, Yang J, Dubeau L, Hu Y, Li R. Yuan B, et al. Among authors: dubeau l. Front Cell Dev Biol. 2021 Apr 9;9:649087. doi: 10.3389/fcell.2021.649087. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33898441 Free PMC article.

9

The TATA-binding protein as a regulator of cellular transformation.

Johnson SA, Dubeau L, White RJ, Johnson DL. Johnson SA, et al. Among authors: dubeau l. Cell Cycle. 2003 Sep-Oct;2(5):442-4. Cell Cycle. 2003. PMID: 12963838 Review.

10

Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice.

Yoo CB, Chuang JC, Byun HM, Egger G, Yang AS, Dubeau L, Long T, Laird PW, Marquez VE, Jones PA. Yoo CB, et al. Among authors: dubeau l. Cancer Prev Res (Phila). 2008 Sep;1(4):233-40. doi: 10.1158/1940-6207.CAPR-07-0008. Epub 2008 Mar 19. Cancer Prev Res (Phila). 2008. PMID: 19138966 Free PMC article.

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