Matsumoto S - Search Results

1

Current status of the development of Ras inhibitors.

Shima F, Matsumoto S, Yoshikawa Y, Kawamura T, Isa M, Kataoka T. Shima F, et al. Among authors: matsumoto s. J Biochem. 2015 Aug;158(2):91-9. doi: 10.1093/jb/mvv060. Epub 2015 Jun 22. J Biochem. 2015. PMID: 26100833 Review.

2

In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction.

Shima F, Yoshikawa Y, Ye M, Araki M, Matsumoto S, Liao J, Hu L, Sugimoto T, Ijiri Y, Takeda A, Nishiyama Y, Sato C, Muraoka S, Tamura A, Osoda T, Tsuda K, Miyakawa T, Fukunishi H, Shimada J, Kumasaka T, Yamamoto M, Kataoka T. Shima F, et al. Among authors: matsumoto s. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8182-7. doi: 10.1073/pnas.1217730110. Epub 2013 Apr 29. Proc Natl Acad Sci U S A. 2013. PMID: 23630290 Free PMC article.

3

Discovery of small-molecule Ras inhibitors that display antitumor activity by interfering with Ras·GTP-effector interaction.

Shima F, Yoshikawa Y, Matsumoto S, Kataoka T. Shima F, et al. Among authors: matsumoto s. Enzymes. 2013;34 Pt. B:1-23. doi: 10.1016/B978-0-12-420146-0.00001-9. Epub 2013 Nov 7. Enzymes. 2013. PMID: 25034098 Review.

4

Molecular Mechanism for Conformational Dynamics of Ras·GTP Elucidated from In-Situ Structural Transition in Crystal.

Matsumoto S, Miyano N, Baba S, Liao J, Kawamura T, Tsuda C, Takeda A, Yamamoto M, Kumasaka T, Kataoka T, Shima F. Matsumoto S, et al. Sci Rep. 2016 May 16;6:25931. doi: 10.1038/srep25931. Sci Rep. 2016. PMID: 27180801 Free PMC article.

5

Structural basis for intramolecular interaction of post-translationally modified H-Ras•GTP prepared by protein ligation.

Ke H, Matsumoto S, Murashima Y, Taniguchi-Tamura H, Miyamoto R, Yoshikawa Y, Tsuda C, Kumasaka T, Mizohata E, Edamatsu H, Kataoka T. Ke H, et al. Among authors: matsumoto s. FEBS Lett. 2017 Aug;591(16):2470-2481. doi: 10.1002/1873-3468.12759. Epub 2017 Aug 2. FEBS Lett. 2017. PMID: 28730604 Free article.

6

Structural transition of solvated H-Ras/GTP revealed by molecular dynamics simulation and local network entropy.

Matsunaga S, Hano Y, Saito Y, Fujimoto KJ, Kumasaka T, Matsumoto S, Kataoka T, Shima F, Tanaka S. Matsunaga S, et al. Among authors: matsumoto s. J Mol Graph Model. 2017 Oct;77:51-63. doi: 10.1016/j.jmgm.2017.07.028. Epub 2017 Jul 29. J Mol Graph Model. 2017. PMID: 28837923

7

Molecular Basis for Allosteric Inhibition of GTP-Bound H-Ras Protein by a Small-Molecule Compound Carrying a Naphthalene Ring.

Matsumoto S, Hiraga T, Hayashi Y, Yoshikawa Y, Tsuda C, Araki M, Neya M, Shima F, Kataoka T. Matsumoto S, et al. Biochemistry. 2018 Sep 11;57(36):5350-5358. doi: 10.1021/acs.biochem.8b00680. Epub 2018 Aug 30. Biochemistry. 2018. PMID: 30141910

8

Oncogenic mutations Q61L and Q61H confer active form-like structural features to the inactive state (state 1) conformation of H-Ras protein.

Matsumoto S, Taniguchi-Tamura H, Araki M, Kawamura T, Miyamoto R, Tsuda C, Shima F, Kumasaka T, Okuno Y, Kataoka T. Matsumoto S, et al. Biochem Biophys Res Commun. 2021 Aug 6;565:85-90. doi: 10.1016/j.bbrc.2021.05.084. Epub 2021 Jun 5. Biochem Biophys Res Commun. 2021. PMID: 34102474

9

Solution structure of the variable-type domain of the receptor for advanced glycation end products: new insight into AGE-RAGE interaction.

Matsumoto S, Yoshida T, Murata H, Harada S, Fujita N, Nakamura S, Yamamoto Y, Watanabe T, Yonekura H, Yamamoto H, Ohkubo T, Kobayashi Y. Matsumoto S, et al. Biochemistry. 2008 Nov 25;47(47):12299-311. doi: 10.1021/bi800910v. Biochemistry. 2008. PMID: 19032093

10

Exploring ligand binding pathways on proteins using hypersound-accelerated molecular dynamics.

Araki M, Matsumoto S, Bekker GJ, Isaka Y, Sagae Y, Kamiya N, Okuno Y. Araki M, et al. Among authors: matsumoto s. Nat Commun. 2021 May 14;12(1):2793. doi: 10.1038/s41467-021-23157-1. Nat Commun. 2021. PMID: 33990583 Free PMC article.

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