Brugman MH - Search Results

1

Inhibition of Thrombopoietin/Mpl Signaling in Adult Hematopoiesis Identifies New Candidates for Hematopoietic Stem Cell Maintenance.

Kohlscheen S, Wintterle S, Schwarzer A, Kamp C, Brugman MH, Breuer DC, Büsche G, Baum C, Modlich U. Kohlscheen S, et al. Among authors: brugman mh. PLoS One. 2015 Jul 6;10(7):e0131866. doi: 10.1371/journal.pone.0131866. eCollection 2015. PLoS One. 2015. PMID: 26147434 Free PMC article.

2

Lentiviral gene transfer regenerates hematopoietic stem cells in a mouse model for Mpl-deficient aplastic anemia.

Heckl D, Wicke DC, Brugman MH, Meyer J, Schambach A, Büsche G, Ballmaier M, Baum C, Modlich U. Heckl D, et al. Among authors: brugman mh. Blood. 2011 Apr 7;117(14):3737-47. doi: 10.1182/blood-2010-09-308262. Epub 2011 Feb 2. Blood. 2011. PMID: 21289307 Free article.

3

Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways.

Kustikova OS, Geiger H, Li Z, Brugman MH, Chambers SM, Shaw CA, Pike-Overzet K, de Ridder D, Staal FJ, von Keudell G, Cornils K, Nattamai KJ, Modlich U, Wagemaker G, Goodell MA, Fehse B, Baum C. Kustikova OS, et al. Among authors: brugman mh. Blood. 2007 Mar 1;109(5):1897-907. doi: 10.1182/blood-2006-08-044156. Epub 2006 Nov 21. Blood. 2007. PMID: 17119121 Free PMC article.

4

Polyclonal fluctuation of lentiviral vector-transduced and expanded murine hematopoietic stem cells.

Maetzig T, Brugman MH, Bartels S, Heinz N, Kustikova OS, Modlich U, Li Z, Galla M, Schiedlmeier B, Schambach A, Baum C. Maetzig T, et al. Among authors: brugman mh. Blood. 2011 Mar 17;117(11):3053-64. doi: 10.1182/blood-2010-08-303222. Epub 2011 Jan 19. Blood. 2011. PMID: 21248062 Free article.

5

Alpharetroviral self-inactivating vectors: long-term transgene expression in murine hematopoietic cells and low genotoxicity.

Suerth JD, Maetzig T, Brugman MH, Heinz N, Appelt JU, Kaufmann KB, Schmidt M, Grez M, Modlich U, Baum C, Schambach A. Suerth JD, et al. Among authors: brugman mh. Mol Ther. 2012 May;20(5):1022-32. doi: 10.1038/mt.2011.309. Epub 2012 Feb 14. Mol Ther. 2012. PMID: 22334016 Free PMC article.

6

Insertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors.

Modlich U, Navarro S, Zychlinski D, Maetzig T, Knoess S, Brugman MH, Schambach A, Charrier S, Galy A, Thrasher AJ, Bueren J, Baum C. Modlich U, et al. Among authors: brugman mh. Mol Ther. 2009 Nov;17(11):1919-28. doi: 10.1038/mt.2009.179. Epub 2009 Aug 11. Mol Ther. 2009. PMID: 19672245 Free PMC article.

7

Evaluating a ligation-mediated PCR and pyrosequencing method for the detection of clonal contribution in polyclonal retrovirally transduced samples.

Brugman MH, Suerth JD, Rothe M, Suerbaum S, Schambach A, Modlich U, Kustikova O, Baum C. Brugman MH, et al. Hum Gene Ther Methods. 2013 Apr;24(2):68-79. doi: 10.1089/hgtb.2012.175. Epub 2013 Mar 14. Hum Gene Ther Methods. 2013. PMID: 23384086 Free PMC article.

8

The genomic risk of somatic gene therapy.

Kustikova O, Brugman M, Baum C. Kustikova O, et al. Semin Cancer Biol. 2010 Aug;20(4):269-78. doi: 10.1016/j.semcancer.2010.06.003. Epub 2010 Jul 1. Semin Cancer Biol. 2010. PMID: 20600920 Review.

9

Activation of Evi1 inhibits cell cycle progression and differentiation of hematopoietic progenitor cells.

Kustikova OS, Schwarzer A, Stahlhut M, Brugman MH, Neumann T, Yang M, Li Z, Schambach A, Heinz N, Gerdes S, Roeder I, Ha TC, Steinemann D, Schlegelberger B, Baum C. Kustikova OS, et al. Among authors: brugman mh. Leukemia. 2013 Apr;27(5):1127-38. doi: 10.1038/leu.2012.355. Epub 2012 Dec 5. Leukemia. 2013. PMID: 23212151

10

Cell-intrinsic and vector-related properties cooperate to determine the incidence and consequences of insertional mutagenesis.

Kustikova OS, Schiedlmeier B, Brugman MH, Stahlhut M, Bartels S, Li Z, Baum C. Kustikova OS, et al. Among authors: brugman mh. Mol Ther. 2009 Sep;17(9):1537-47. doi: 10.1038/mt.2009.134. Epub 2009 Jun 16. Mol Ther. 2009. PMID: 19532134 Free PMC article.

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