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A functional variant that affects exon-skipping and protein expression of SP140 as genetic mechanism predisposing to multiple sclerosis.
Matesanz F, Potenciano V, Fedetz M, Ramos-Mozo P, Abad-Grau Mdel M, Karaky M, Barrionuevo C, Izquierdo G, Ruiz-Peña JL, García-Sánchez MI, Lucas M, Fernández Ó, Leyva L, Otaegui D, Muñoz-Culla M, Olascoaga J, Vandenbroeck K, Alloza I, Astobiza I, Antigüedad A, Villar LM, Álvarez-Cermeño JC, Malhotra S, Comabella M, Montalban X, Saiz A, Blanco Y, Arroyo R, Varadé J, Urcelay E, Alcina A. Matesanz F, et al. Among authors: montalban x. Hum Mol Genet. 2015 Oct 1;24(19):5619-27. doi: 10.1093/hmg/ddv256. Epub 2015 Jul 7. Hum Mol Genet. 2015. PMID: 26152201
[Natural interferon-beta in the treatment of relapsing-remitting multiple sclerosis: a multicenter, randomized, MRI-based, phase II clinical trial].
Fernández O, Antigüedad A, Arbizu T, Burgués S, Capdevila A, de Castro P, Correa de Sá JC, García-Merino JA, Izquierdo G, Magalhaes A, Montalbán X, Zarranz JJ. Fernández O, et al. Among authors: montalban x. Rev Neurol. 1999 Dec 16-31;29(12):1093-9. Rev Neurol. 1999. PMID: 10652728 Clinical Trial. Spanish.
A genomic screen of Spanish multiple sclerosis patients reveals multiple loci associated with the disease.
Goertsches R, Villoslada P, Comabella M, Montalban X, Navarro A, de la Concha EG, Arroyo R, Lopez de Munain A, Otaegui D, Palacios R, Perez-Tur J, Jonasdottir A, Benediktsson K, Fossdal R, Sawcer S, Setakis E, Compston A; Spanish MS Genetics Group. Goertsches R, et al. Among authors: montalban x. J Neuroimmunol. 2003 Oct;143(1-2):124-8. doi: 10.1016/j.jneuroim.2003.08.026. J Neuroimmunol. 2003. PMID: 14575929
801 results