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H3K36 methylation promotes longevity by enhancing transcriptional fidelity.
Sen P, Dang W, Donahue G, Dai J, Dorsey J, Cao X, Liu W, Cao K, Perry R, Lee JY, Wasko BM, Carr DT, He C, Robison B, Wagner J, Gregory BD, Kaeberlein M, Kennedy BK, Boeke JD, Berger SL. Sen P, et al. Genes Dev. 2015 Jul 1;29(13):1362-76. doi: 10.1101/gad.263707.115. Genes Dev. 2015. PMID: 26159996 Free PMC article.
Epigenetic Mechanisms of Longevity and Aging.
Sen P, Shah PP, Nativio R, Berger SL. Sen P, et al. Cell. 2016 Aug 11;166(4):822-839. doi: 10.1016/j.cell.2016.07.050. Cell. 2016. PMID: 27518561 Free PMC article. Review.
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis.
Lin-Shiao E, Lan Y, Coradin M, Anderson A, Donahue G, Simpson CL, Sen P, Saffie R, Busino L, Garcia BA, Berger SL, Capell BC. Lin-Shiao E, et al. Among authors: sen p. Genes Dev. 2018 Jan 15;32(2):181-193. doi: 10.1101/gad.306241.117. Epub 2018 Feb 12. Genes Dev. 2018. PMID: 29440247 Free PMC article.
Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca2+-NFAT signaling.
Lee JV, Berry CT, Kim K, Sen P, Kim T, Carrer A, Trefely S, Zhao S, Fernandez S, Barney LE, Schwartz AD, Peyton SR, Snyder NW, Berger SL, Freedman BD, Wellen KE. Lee JV, et al. Among authors: sen p. Genes Dev. 2018 Apr 1;32(7-8):497-511. doi: 10.1101/gad.311027.117. Epub 2018 Apr 19. Genes Dev. 2018. PMID: 29674394 Free PMC article.
Cytoplasmic chromatin triggers inflammation in senescence and cancer.
Dou Z, Ghosh K, Vizioli MG, Zhu J, Sen P, Wangensteen KJ, Simithy J, Lan Y, Lin Y, Zhou Z, Capell BC, Xu C, Xu M, Kieckhaefer JE, Jiang T, Shoshkes-Carmel M, Tanim KMAA, Barber GN, Seykora JT, Millar SE, Kaestner KH, Garcia BA, Adams PD, Berger SL. Dou Z, et al. Among authors: sen p. Nature. 2017 Oct 19;550(7676):402-406. doi: 10.1038/nature24050. Epub 2017 Oct 4. Nature. 2017. PMID: 28976970 Free PMC article.
The senescent cell epigenome.
Yang N, Sen P. Yang N, et al. Among authors: sen p. Aging (Albany NY). 2018 Nov 3;10(11):3590-3609. doi: 10.18632/aging.101617. Aging (Albany NY). 2018. PMID: 30391936 Free PMC article. Review.
Gene body DNA hydroxymethylation restricts the magnitude of transcriptional changes during aging.
Occean JR, Yang N, Sun Y, Dawkins MS, Munk R, Belair C, Dar S, Anerillas C, Wang L, Shi C, Dunn C, Bernier M, Price NL, Kim JS, Cui CY, Fan J, Bhattacharyya M, De S, Maragkakis M, de Cabo R, Sidoli S, Sen P. Occean JR, et al. Among authors: sen p. Nat Commun. 2024 Jul 28;15(1):6357. doi: 10.1038/s41467-024-50725-y. Nat Commun. 2024. PMID: 39069555 Free PMC article.
1,544 results