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Page 1
Genetic Deletion and Pharmacological Inhibition of PI3K γ Reduces Neutrophilic Airway Inflammation and Lung Damage in Mice with Cystic Fibrosis-Like Lung Disease.
Galluzzo M, Ciraolo E, Lucattelli M, Hoxha E, Ulrich M, Campa CC, Lungarella G, Doring G, Zhou-Suckow Z, Mall M, Hirsch E, De Rose V. Galluzzo M, et al. Among authors: campa cc. Mediators Inflamm. 2015;2015:545417. doi: 10.1155/2015/545417. Epub 2015 Jun 21. Mediators Inflamm. 2015. PMID: 26185363 Free PMC article.
PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium function.
Franco I, Gulluni F, Campa CC, Costa C, Margaria JP, Ciraolo E, Martini M, Monteyne D, De Luca E, Germena G, Posor Y, Maffucci T, Marengo S, Haucke V, Falasca M, Perez-Morga D, Boletta A, Merlo GR, Hirsch E. Franco I, et al. Among authors: campa cc. Dev Cell. 2014 Mar 31;28(6):647-58. doi: 10.1016/j.devcel.2014.01.022. Dev Cell. 2014. PMID: 24697898 Free PMC article.
Crossroads of PI3K and Rac pathways.
Campa CC, Ciraolo E, Ghigo A, Germena G, Hirsch E. Campa CC, et al. Small GTPases. 2015;6(2):71-80. doi: 10.4161/21541248.2014.989789. Epub 2015 May 5. Small GTPases. 2015. PMID: 25942647 Free PMC article. Review.
Phosphoinositide 3-Kinase-C2α Regulates Polycystin-2 Ciliary Entry and Protects against Kidney Cyst Formation.
Franco I, Margaria JP, De Santis MC, Ranghino A, Monteyne D, Chiaravalli M, Pema M, Campa CC, Ratto E, Gulluni F, Perez-Morga D, Somlo S, Merlo GR, Boletta A, Hirsch E. Franco I, et al. Among authors: campa cc. J Am Soc Nephrol. 2016 Apr;27(4):1135-44. doi: 10.1681/ASN.2014100967. Epub 2015 Aug 13. J Am Soc Nephrol. 2016. PMID: 26271513 Free PMC article.
How PI3K-derived lipids control cell division.
Campa CC, Martini M, De Santis MC, Hirsch E. Campa CC, et al. Front Cell Dev Biol. 2015 Sep 30;3:61. doi: 10.3389/fcell.2015.00061. eCollection 2015. Front Cell Dev Biol. 2015. PMID: 26484344 Free PMC article. Review.
Rac signal adaptation controls neutrophil mobilization from the bone marrow.
Campa CC, Germena G, Ciraolo E, Copperi F, Sapienza A, Franco I, Ghigo A, Camporeale A, Di Savino A, Martini M, Perino A, Megens RT, Kurz AR, Scheiermann C, Sperandio M, Gamba A, Hirsch E. Campa CC, et al. Sci Signal. 2016 Dec 20;9(459):ra124. doi: 10.1126/scisignal.aah5882. Sci Signal. 2016. PMID: 27999173
Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs.
Pirali T, Ciraolo E, Aprile S, Massarotti A, Berndt A, Griglio A, Serafini M, Mercalli V, Landoni C, Campa CC, Margaria JP, Silva RL, Grosa G, Sorba G, Williams R, Hirsch E, Tron GC. Pirali T, et al. Among authors: campa cc. ChemMedChem. 2017 Sep 21;12(18):1542-1554. doi: 10.1002/cmdc.201700340. Epub 2017 Aug 31. ChemMedChem. 2017. PMID: 28857471 Free PMC article.
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