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Genetic Deletion and Pharmacological Inhibition of PI3K γ Reduces Neutrophilic Airway Inflammation and Lung Damage in Mice with Cystic Fibrosis-Like Lung Disease.
Galluzzo M, Ciraolo E, Lucattelli M, Hoxha E, Ulrich M, Campa CC, Lungarella G, Doring G, Zhou-Suckow Z, Mall M, Hirsch E, De Rose V. Galluzzo M, et al. Among authors: hirsch e. Mediators Inflamm. 2015;2015:545417. doi: 10.1155/2015/545417. Epub 2015 Jun 21. Mediators Inflamm. 2015. PMID: 26185363 Free PMC article.
Negative feedback regulation of Rac in leukocytes from mice expressing a constitutively active phosphatidylinositol 3-kinase gamma.
Costa C, Barberis L, Ambrogio C, Manazza AD, Patrucco E, Azzolino O, Neilsen PO, Ciraolo E, Altruda F, Prestwich GD, Chiarle R, Wymann M, Ridley A, Hirsch E. Costa C, et al. Among authors: hirsch e. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14354-9. doi: 10.1073/pnas.0703175104. Epub 2007 Aug 24. Proc Natl Acad Sci U S A. 2007. PMID: 17720808 Free PMC article.
Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development.
Ciraolo E, Iezzi M, Marone R, Marengo S, Curcio C, Costa C, Azzolino O, Gonella C, Rubinetto C, Wu H, Dastrù W, Martin EL, Silengo L, Altruda F, Turco E, Lanzetti L, Musiani P, Rückle T, Rommel C, Backer JM, Forni G, Wymann MP, Hirsch E. Ciraolo E, et al. Among authors: hirsch e. Sci Signal. 2008 Sep 9;1(36):ra3. doi: 10.1126/scisignal.1161577. Sci Signal. 2008. PMID: 18780892 Free PMC article.
Twice upon a time: PI3K's secret double life exposed.
Hirsch E, Braccini L, Ciraolo E, Morello F, Perino A. Hirsch E, et al. Trends Biochem Sci. 2009 May;34(5):244-8. doi: 10.1016/j.tibs.2009.02.003. Epub 2009 Apr 17. Trends Biochem Sci. 2009. PMID: 19376709 Review.
Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility.
Ciraolo E, Morello F, Hobbs RM, Wolf F, Marone R, Iezzi M, Lu X, Mengozzi G, Altruda F, Sorba G, Guan K, Pandolfi PP, Wymann MP, Hirsch E. Ciraolo E, et al. Among authors: hirsch e. Mol Biol Cell. 2010 Mar 1;21(5):704-11. doi: 10.1091/mbc.e09-08-0744. Epub 2010 Jan 6. Mol Biol Cell. 2010. PMID: 20053680 Free PMC article.
1,569 results