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Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia.
Song C, Gowda C, Pan X, Ding Y, Tong Y, Tan BH, Wang H, Muthusami S, Ge Z, Sachdev M, Amin SG, Desai D, Gowda K, Gowda R, Robertson GP, Schjerven H, Muschen M, Payne KJ, Dovat S. Song C, et al. Among authors: sachdev m. Blood. 2015 Oct 8;126(15):1813-22. doi: 10.1182/blood-2015-06-651505. Epub 2015 Jul 28. Blood. 2015. PMID: 26219304 Free PMC article.
Transcriptional Regulation of JARID1B/KDM5B Histone Demethylase by Ikaros, Histone Deacetylase 1 (HDAC1), and Casein Kinase 2 (CK2) in B-cell Acute Lymphoblastic Leukemia.
Wang H, Song C, Ding Y, Pan X, Ge Z, Tan BH, Gowda C, Sachdev M, Muthusami S, Ouyang H, Lai L, Francis OL, Morris CL, Abdel-Azim H, Dorsam G, Xiang M, Payne KJ, Dovat S. Wang H, et al. Among authors: sachdev m. J Biol Chem. 2016 Feb 19;291(8):4004-18. doi: 10.1074/jbc.M115.679332. Epub 2015 Dec 10. J Biol Chem. 2016. PMID: 26655717 Free PMC article.
Casein Kinase II (CK2) as a Therapeutic Target for Hematological Malignancies.
Gowda C, Sachdev M, Muthusami S, Kapadia M, Petrovic-Dovat L, Hartman M, Ding Y, Song C, Payne JL, Tan BH, Dovat S. Gowda C, et al. Among authors: sachdev m. Curr Pharm Des. 2017;23(1):95-107. doi: 10.2174/1381612822666161006154311. Curr Pharm Des. 2017. PMID: 27719640 Review.
232 results