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Systems biology definition of the core proteome of metabolism and expression is consistent with high-throughput data.
Yang L, Tan J, O'Brien EJ, Monk JM, Kim D, Li HJ, Charusanti P, Ebrahim A, Lloyd CJ, Yurkovich JT, Du B, Dräger A, Thomas A, Sun Y, Saunders MA, Palsson BO. Yang L, et al. Among authors: yurkovich jt. Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10810-5. doi: 10.1073/pnas.1501384112. Epub 2015 Aug 10. Proc Natl Acad Sci U S A. 2015. PMID: 26261351 Free PMC article.
Cellular responses to reactive oxygen species are predicted from molecular mechanisms.
Yang L, Mih N, Anand A, Park JH, Tan J, Yurkovich JT, Monk JM, Lloyd CJ, Sandberg TE, Seo SW, Kim D, Sastry AV, Phaneuf P, Gao Y, Broddrick JT, Chen K, Heckmann D, Szubin R, Hefner Y, Feist AM, Palsson BO. Yang L, et al. Among authors: yurkovich jt. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14368-14373. doi: 10.1073/pnas.1905039116. Epub 2019 Jul 3. Proc Natl Acad Sci U S A. 2019. PMID: 31270234 Free PMC article.
The quantitative metabolome is shaped by abiotic constraints.
Akbari A, Yurkovich JT, Zielinski DC, Palsson BO. Akbari A, et al. Among authors: yurkovich jt. Nat Commun. 2021 May 26;12(1):3178. doi: 10.1038/s41467-021-23214-9. Nat Commun. 2021. PMID: 34039963 Free PMC article.
Is the kinetome conserved?
Palsson BO, Yurkovich JT. Palsson BO, et al. Among authors: yurkovich jt. Mol Syst Biol. 2022 Feb;18(2):e10782. doi: 10.15252/msb.202110782. Mol Syst Biol. 2022. PMID: 35188334 Free PMC article.
48 results