Hollfelder F - Search Results

1

Reverse evolution leads to genotypic incompatibility despite functional and active site convergence.

Kaltenbach M, Jackson CJ, Campbell EC, Hollfelder F, Tokuriki N. Kaltenbach M, et al. Among authors: hollfelder f. Elife. 2015 Aug 14;4:e06492. doi: 10.7554/eLife.06492. Elife. 2015. PMID: 26274563 Free PMC article.

2

What makes an enzyme promiscuous?

Babtie A, Tokuriki N, Hollfelder F. Babtie A, et al. Among authors: hollfelder f. Curr Opin Chem Biol. 2010 Apr;14(2):200-7. doi: 10.1016/j.cbpa.2009.11.028. Epub 2010 Jan 18. Curr Opin Chem Biol. 2010. PMID: 20080434 Review.

3

SNAP dendrimers: multivalent protein display on dendrimer-like DNA for directed evolution.

Kaltenbach M, Stein V, Hollfelder F. Kaltenbach M, et al. Among authors: hollfelder f. Chembiochem. 2011 Sep 19;12(14):2208-16. doi: 10.1002/cbic.201100240. Epub 2011 Jul 21. Chembiochem. 2011. PMID: 21780273

4

SNAP display: in vitro protein evolution in microdroplets.

Kaltenbach M, Hollfelder F. Kaltenbach M, et al. Among authors: hollfelder f. Methods Mol Biol. 2012;805:101-11. doi: 10.1007/978-1-61779-379-0_7. Methods Mol Biol. 2012. PMID: 22094803

5

Assembling linear DNA templates for in vitro transcription and translation.

Stein V, Kaltenbach M, Hollfelder F. Stein V, et al. Among authors: hollfelder f. Methods Mol Biol. 2012;815:67-78. doi: 10.1007/978-1-61779-424-7_6. Methods Mol Biol. 2012. PMID: 22130984

6

A simple method to evaluate the biochemical compatibility of oil/surfactant mixtures for experiments in microdroplets.

Kaltenbach M, Devenish SR, Hollfelder F. Kaltenbach M, et al. Among authors: hollfelder f. Lab Chip. 2012 Oct 21;12(20):4185-92. doi: 10.1039/c2lc40281e. Lab Chip. 2012. PMID: 22885600

7

Droplets as reaction compartments for protein nanotechnology.

Devenish SR, Kaltenbach M, Fischlechner M, Hollfelder F. Devenish SR, et al. Among authors: hollfelder f. Methods Mol Biol. 2013;996:269-86. doi: 10.1007/978-1-62703-354-1_16. Methods Mol Biol. 2013. PMID: 23504430 Review.

8

An experimental framework for improved selection of binding proteins using SNAP display.

Houlihan G, Gatti-Lafranconi P, Kaltenbach M, Lowe D, Hollfelder F. Houlihan G, et al. Among authors: hollfelder f. J Immunol Methods. 2014 Mar;405:47-56. doi: 10.1016/j.jim.2014.01.006. Epub 2014 Jan 20. J Immunol Methods. 2014. PMID: 24456628 Free article.

9

The role of protein dynamics in the evolution of new enzyme function.

Campbell E, Kaltenbach M, Correy GJ, Carr PD, Porebski BT, Livingstone EK, Afriat-Jurnou L, Buckle AM, Weik M, Hollfelder F, Tokuriki N, Jackson CJ. Campbell E, et al. Among authors: hollfelder f. Nat Chem Biol. 2016 Nov;12(11):944-950. doi: 10.1038/nchembio.2175. Epub 2016 Sep 12. Nat Chem Biol. 2016. PMID: 27618189

10

Functional Trade-Offs in Promiscuous Enzymes Cannot Be Explained by Intrinsic Mutational Robustness of the Native Activity.

Kaltenbach M, Emond S, Hollfelder F, Tokuriki N. Kaltenbach M, et al. Among authors: hollfelder f. PLoS Genet. 2016 Oct 7;12(10):e1006305. doi: 10.1371/journal.pgen.1006305. eCollection 2016 Oct. PLoS Genet. 2016. PMID: 27716796 Free PMC article.

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