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Unbiased proteomics identifies plasminogen activator inhibitor-1 as a negative regulator of endothelial nitric oxide synthase.
Garcia V, Park EJ, Siragusa M, Frohlich F, Mahfuzul Haque M, Pascale JV, Heberlein KR, Isakson BE, Stuehr DJ, Sessa WC. Garcia V, et al. Among authors: siragusa m. Proc Natl Acad Sci U S A. 2020 Apr 28;117(17):9497-9507. doi: 10.1073/pnas.1918761117. Epub 2020 Apr 16. Proc Natl Acad Sci U S A. 2020. PMID: 32300005 Free PMC article.
Endothelial miR-17∼92 cluster negatively regulates arteriogenesis via miRNA-19 repression of WNT signaling.
Landskroner-Eiger S, Qiu C, Perrotta P, Siragusa M, Lee MY, Ulrich V, Luciano AK, Zhuang ZW, Corti F, Simons M, Montgomery RL, Wu D, Yu J, Sessa WC. Landskroner-Eiger S, et al. Among authors: siragusa m. Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):12812-7. doi: 10.1073/pnas.1507094112. Epub 2015 Sep 28. Proc Natl Acad Sci U S A. 2015. PMID: 26417068 Free PMC article.
Loss of Endothelial Cytochrome P450 Reductase Induces Vascular Dysfunction in Mice.
Malacarne PF, Ratiu C, Gajos-Draus A, Müller N, Lopez M, Pflüger-Müller B, Ding X, Warwick T, Oo J, Siragusa M, Angioni C, Günther S, Weigert A, Geißlinger G, Lütjohann D, Schunck WH, Fleming I, Brandes RP, Rezende F. Malacarne PF, et al. Among authors: siragusa m. Hypertension. 2022 Jun;79(6):1216-1226. doi: 10.1161/HYPERTENSIONAHA.121.18752. Epub 2022 Mar 31. Hypertension. 2022. PMID: 35354305
Zeb1-Hdac2-eNOS circuitry identifies early cardiovascular precursors in naive mouse embryonic stem cells.
Cencioni C, Spallotta F, Savoia M, Kuenne C, Guenther S, Re A, Wingert S, Rehage M, Sürün D, Siragusa M, Smith JG, Schnütgen F, von Melchner H, Rieger MA, Martelli F, Riccio A, Fleming I, Braun T, Zeiher AM, Farsetti A, Gaetano C. Cencioni C, et al. Among authors: siragusa m. Nat Commun. 2018 Mar 29;9(1):1281. doi: 10.1038/s41467-018-03668-0. Nat Commun. 2018. PMID: 29599503 Free PMC article.
Critical role of tissue kallikrein in vessel formation and maturation: implications for therapeutic revascularization.
Stone OA, Richer C, Emanueli C, van Weel V, Quax PH, Katare R, Kraenkel N, Campagnolo P, Barcelos LS, Siragusa M, Sala-Newby GB, Baldessari D, Mione M, Vincent MP, Benest AV, Al Haj Zen A, Gonzalez J, Bates DO, Alhenc-Gelas F, Madeddu P. Stone OA, et al. Among authors: siragusa m. Arterioscler Thromb Vasc Biol. 2009 May;29(5):657-64. doi: 10.1161/ATVBAHA.108.182139. Epub 2009 Jan 22. Arterioscler Thromb Vasc Biol. 2009. PMID: 19164804 Free PMC article.
Phosphoinositide 3-kinase gamma gene knockout impairs postischemic neovascularization and endothelial progenitor cell functions.
Madeddu P, Kraenkel N, Barcelos LS, Siragusa M, Campagnolo P, Oikawa A, Caporali A, Herman A, Azzolino O, Barberis L, Perino A, Damilano F, Emanueli C, Hirsch E. Madeddu P, et al. Among authors: siragusa m. Arterioscler Thromb Vasc Biol. 2008 Jan;28(1):68-76. doi: 10.1161/ATVBAHA.107.145573. Epub 2007 Oct 25. Arterioscler Thromb Vasc Biol. 2008. PMID: 17962628 Free PMC article.
137 results