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PHD1 regulates p53-mediated colorectal cancer chemoresistance.
Deschoemaeker S, Di Conza G, Lilla S, Martín-Pérez R, Mennerich D, Boon L, Hendrikx S, Maddocks OD, Marx C, Radhakrishnan P, Prenen H, Schneider M, Myllyharju J, Kietzmann T, Vousden KH, Zanivan S, Mazzone M. Deschoemaeker S, et al. Among authors: schneider m. EMBO Mol Med. 2015 Oct;7(10):1350-65. doi: 10.15252/emmm.201505492. EMBO Mol Med. 2015. PMID: 26290450 Free PMC article.
Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism.
Aragonés J, Schneider M, Van Geyte K, Fraisl P, Dresselaers T, Mazzone M, Dirkx R, Zacchigna S, Lemieux H, Jeoung NH, Lambrechts D, Bishop T, Lafuste P, Diez-Juan A, Harten SK, Van Noten P, De Bock K, Willam C, Tjwa M, Grosfeld A, Navet R, Moons L, Vandendriessche T, Deroose C, Wijeyekoon B, Nuyts J, Jordan B, Silasi-Mansat R, Lupu F, Dewerchin M, Pugh C, Salmon P, Mortelmans L, Gallez B, Gorus F, Buyse J, Sluse F, Harris RA, Gnaiger E, Hespel P, Van Hecke P, Schuit F, Van Veldhoven P, Ratcliffe P, Baes M, Maxwell P, Carmeliet P. Aragonés J, et al. Among authors: schneider m. Nat Genet. 2008 Feb;40(2):170-80. doi: 10.1038/ng.2007.62. Epub 2008 Jan 6. Nat Genet. 2008. PMID: 18176562 Free article.
Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury.
Schneider M, Van Geyte K, Fraisl P, Kiss J, Aragonés J, Mazzone M, Mairbäurl H, De Bock K, Jeoung NH, Mollenhauer M, Georgiadou M, Bishop T, Roncal C, Sutherland A, Jordan B, Gallez B, Weitz J, Harris RA, Maxwell P, Baes M, Ratcliffe P, Carmeliet P. Schneider M, et al. Gastroenterology. 2010 Mar;138(3):1143-54.e1-2. doi: 10.1053/j.gastro.2009.09.057. Epub 2009 Oct 8. Gastroenterology. 2010. PMID: 19818783 Free article.
Overexpression of ZEB2 at the invasion front of colorectal cancer is an independent prognostic marker and regulates tumor invasion in vitro.
Kahlert C, Lahes S, Radhakrishnan P, Dutta S, Mogler C, Herpel E, Brand K, Steinert G, Schneider M, Mollenhauer M, Reissfelder C, Klupp F, Fritzmann J, Wunder C, Benner A, Kloor M, Huth C, Contin P, Ulrich A, Koch M, Weitz J. Kahlert C, et al. Among authors: schneider m. Clin Cancer Res. 2011 Dec 15;17(24):7654-63. doi: 10.1158/1078-0432.CCR-10-2816. Epub 2011 Oct 31. Clin Cancer Res. 2011. PMID: 22042972
Loss of the oxygen sensor PHD3 enhances the innate immune response to abdominal sepsis.
Kiss J, Mollenhauer M, Walmsley SR, Kirchberg J, Radhakrishnan P, Niemietz T, Dudda J, Steinert G, Whyte MK, Carmeliet P, Mazzone M, Weitz J, Schneider M. Kiss J, et al. Among authors: schneider m. J Immunol. 2012 Aug 15;189(4):1955-65. doi: 10.4049/jimmunol.1103471. Epub 2012 Jul 11. J Immunol. 2012. PMID: 22786772 Free PMC article.
Prolyl Hydroxylase 3 Attenuates MCL-1-Mediated ATP Production to Suppress the Metastatic Potential of Colorectal Cancer Cells.
Radhakrishnan P, Ruh N, Harnoss JM, Kiss J, Mollenhauer M, Scherr AL, Platzer LK, Schmidt T, Podar K, Opferman JT, Weitz J, Schulze-Bergkamen H, Koehler BC, Ulrich A, Schneider M. Radhakrishnan P, et al. Among authors: schneider m. Cancer Res. 2016 Apr 15;76(8):2219-30. doi: 10.1158/0008-5472.CAN-15-1474. Epub 2016 Feb 26. Cancer Res. 2016. PMID: 26921340
TAM receptors Tyro3 and Mer as novel targets in colorectal cancer.
Schmitz R, Valls AF, Yerbes R, von Richter S, Kahlert C, Loges S, Weitz J, Schneider M, Ruiz de Almodovar C, Ulrich A, Schmidt T. Schmitz R, et al. Among authors: schneider m. Oncotarget. 2016 Aug 30;7(35):56355-56370. doi: 10.18632/oncotarget.10889. Oncotarget. 2016. PMID: 27486820 Free PMC article.
7,413 results