MacDonald ME - Search Results

1

HdhQ111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid Accumulation.

Carroll JB, Deik A, Fossale E, Weston RM, Guide JR, Arjomand J, Kwak S, Clish CB, MacDonald ME. Carroll JB, et al. Among authors: macdonald me. PLoS One. 2015 Aug 21;10(8):e0134465. doi: 10.1371/journal.pone.0134465. eCollection 2015. PLoS One. 2015. PMID: 26295712 Free PMC article.

2

Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice.

Wheeler VC, White JK, Gutekunst CA, Vrbanac V, Weaver M, Li XJ, Li SH, Yi H, Vonsattel JP, Gusella JF, Hersch S, Auerbach W, Joyner AL, MacDonald ME. Wheeler VC, et al. Among authors: macdonald me. Hum Mol Genet. 2000 Mar 1;9(4):503-13. doi: 10.1093/hmg/9.4.503. Hum Mol Genet. 2000. PMID: 10699173

3

Identification of a presymptomatic molecular phenotype in Hdh CAG knock-in mice.

Fossale E, Wheeler VC, Vrbanac V, Lebel LA, Teed A, Mysore JS, Gusella JF, MacDonald ME, Persichetti F. Fossale E, et al. Among authors: macdonald me. Hum Mol Genet. 2002 Sep 15;11(19):2233-41. doi: 10.1093/hmg/11.19.2233. Hum Mol Genet. 2002. PMID: 12217951

4

Specific progressive cAMP reduction implicates energy deficit in presymptomatic Huntington's disease knock-in mice.

Gines S, Seong IS, Fossale E, Ivanova E, Trettel F, Gusella JF, Wheeler VC, Persichetti F, MacDonald ME. Gines S, et al. Among authors: macdonald me. Hum Mol Genet. 2003 Mar 1;12(5):497-508. doi: 10.1093/hmg/ddg046. Hum Mol Genet. 2003. PMID: 12588797

5

Membrane trafficking and mitochondrial abnormalities precede subunit c deposition in a cerebellar cell model of juvenile neuronal ceroid lipofuscinosis.

Fossale E, Wolf P, Espinola JA, Lubicz-Nawrocka T, Teed AM, Gao H, Rigamonti D, Cattaneo E, MacDonald ME, Cotman SL. Fossale E, et al. Among authors: macdonald me. BMC Neurosci. 2004 Dec 10;5:57. doi: 10.1186/1471-2202-5-57. BMC Neurosci. 2004. PMID: 15588329 Free PMC article.

6

HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism.

Seong IS, Ivanova E, Lee JM, Choo YS, Fossale E, Anderson M, Gusella JF, Laramie JM, Myers RH, Lesort M, MacDonald ME. Seong IS, et al. Among authors: macdonald me. Hum Mol Genet. 2005 Oct 1;14(19):2871-80. doi: 10.1093/hmg/ddi319. Epub 2005 Aug 22. Hum Mol Genet. 2005. PMID: 16115812

7

Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1.

Shibata M, Lu T, Furuya T, Degterev A, Mizushima N, Yoshimori T, MacDonald M, Yankner B, Yuan J. Shibata M, et al. J Biol Chem. 2006 May 19;281(20):14474-85. doi: 10.1074/jbc.M600364200. Epub 2006 Mar 6. J Biol Chem. 2006. PMID: 16522639 Free article.

8

Genetic background modifies nuclear mutant huntingtin accumulation and HD CAG repeat instability in Huntington's disease knock-in mice.

Lloret A, Dragileva E, Teed A, Espinola J, Fossale E, Gillis T, Lopez E, Myers RH, MacDonald ME, Wheeler VC. Lloret A, et al. Among authors: macdonald me. Hum Mol Genet. 2006 Jun 15;15(12):2015-24. doi: 10.1093/hmg/ddl125. Epub 2006 May 10. Hum Mol Genet. 2006. PMID: 16687439

9

Autophagy is disrupted in a knock-in mouse model of juvenile neuronal ceroid lipofuscinosis.

Cao Y, Espinola JA, Fossale E, Massey AC, Cuervo AM, MacDonald ME, Cotman SL. Cao Y, et al. Among authors: macdonald me. J Biol Chem. 2006 Jul 21;281(29):20483-93. doi: 10.1074/jbc.M602180200. Epub 2006 May 19. J Biol Chem. 2006. PMID: 16714284 Free article.

10

Discovery of bioactive small-molecule inhibitor of poly adp-ribose polymerase: implications for energy-deficient cells.

Altmann SM, Muryshev A, Fossale E, Maxwell MM, Norflus FN, Fox J, Hersch SM, Young AB, MacDonald ME, Abagyan R, Kazantsev AG. Altmann SM, et al. Among authors: macdonald me. Chem Biol. 2006 Jul;13(7):765-70. doi: 10.1016/j.chembiol.2006.05.012. Chem Biol. 2006. PMID: 16873024

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