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Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo.
Caserta E, Egriboz O, Wang H, Martin C, Koivisto C, Pecót T, Kladney RD, Shen C, Shim KS, Pham T, Karikomi MK, Mauntel MJ, Majumder S, Cuitino MC, Tang X, Srivastava A, Yu L, Wallace J, Mo X, Park M, Fernandez SA, Pilarski R, La Perle KM, Rosol TJ, Coppola V, Castrillon DH, Timmers C, Cohn DE, O'Malley DM, Backes F, Suarez AA, Goodfellow P, Chamberlin HM, Macrae ER, Shapiro CL, Ostrowski MC, Leone G. Caserta E, et al. Among authors: srivastava a. Genes Dev. 2015 Aug 15;29(16):1707-20. doi: 10.1101/gad.262568.115. Genes Dev. 2015. PMID: 26302789 Free PMC article.
Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles.
Liu H, Tang X, Srivastava A, Pécot T, Daniel P, Hemmelgarn B, Reyes S, Fackler N, Bajwa A, Kladney R, Koivisto C, Chen Z, Wang Q, Huang K, Machiraju R, Sáenz-Robles MT, Cantalupo P, Pipas JM, Leone G. Liu H, et al. Among authors: srivastava a. Nat Cell Biol. 2015 Aug;17(8):1036-48. doi: 10.1038/ncb3210. Epub 2015 Jul 20. Nat Cell Biol. 2015. PMID: 26192440 Free PMC article.
Transcriptome regulation and chromatin occupancy by E2F3 and MYC in mice.
Tang X, Liu H, Srivastava A, Pécot T, Chen Z, Wang Q, Huang K, Sáenz-Robles MT, Cantalupo P, Pipas J, Leone G. Tang X, et al. Among authors: srivastava a. Sci Data. 2016 Feb 16;3:160008. doi: 10.1038/sdata.2016.8. Sci Data. 2016. PMID: 26881867 Free PMC article.
E2f8 mediates tumor suppression in postnatal liver development.
Kent LN, Rakijas JB, Pandit SK, Westendorp B, Chen HZ, Huntington JT, Tang X, Bae S, Srivastava A, Senapati S, Koivisto C, Martin CK, Cuitino MC, Perez M, Clouse JM, Chokshi V, Shinde N, Kladney R, Sun D, Perez-Castro A, Matondo RB, Nantasanti S, Mokry M, Huang K, Machiraju R, Fernandez S, Rosol TJ, Coppola V, Pohar KS, Pipas JM, Schmidt CR, de Bruin A, Leone G. Kent LN, et al. Among authors: srivastava a. J Clin Invest. 2016 Aug 1;126(8):2955-69. doi: 10.1172/JCI85506. Epub 2016 Jul 25. J Clin Invest. 2016. PMID: 27454291 Free PMC article.
Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma.
Kent LN, Bae S, Tsai SY, Tang X, Srivastava A, Koivisto C, Martin CK, Ridolfi E, Miller GC, Zorko SM, Plevris E, Hadjiyannis Y, Perez M, Nolan E, Kladney R, Westendorp B, de Bruin A, Fernandez S, Rosol TJ, Pohar KS, Pipas JM, Leone G. Kent LN, et al. Among authors: srivastava a. J Clin Invest. 2017 Mar 1;127(3):830-842. doi: 10.1172/JCI87583. Epub 2017 Jan 30. J Clin Invest. 2017. PMID: 28134624 Free PMC article.
DISCOVERY OF MOLECULARLY TARGETED THERAPIES.
Regan K, Abrams Z, Sharpnack M, Srivastava A, Huang K, Shah N, Payne PR. Regan K, et al. Among authors: srivastava a. Pac Symp Biocomput. 2016;21:1-8. Pac Symp Biocomput. 2016. PMID: 26776168 Free PMC article. No abstract available.
Transcriptome and genome evolution during HER2-amplified breast neoplasia.
Lu P, Foley J, Zhu C, McNamara K, Sirinukunwattana K, Vennam S, Varma S, Fehri H, Srivastava A, Zhu S, Rittscher J, Mallick P, Curtis C, West R. Lu P, et al. Among authors: srivastava a. Breast Cancer Res. 2021 Jul 15;23(1):73. doi: 10.1186/s13058-021-01451-6. Breast Cancer Res. 2021. PMID: 34266469 Free PMC article.
7,322 results