Gostissa M - Search Results

1

Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.

Dong J, Panchakshari RA, Zhang T, Zhang Y, Hu J, Volpi SA, Meyers RM, Ho YJ, Du Z, Robbiani DF, Meng F, Gostissa M, Nussenzweig MC, Manis JP, Alt FW. Dong J, et al. Among authors: gostissa m. Nature. 2015 Sep 3;525(7567):134-139. doi: 10.1038/nature14970. Epub 2015 Aug 26. Nature. 2015. PMID: 26308889 Free PMC article.

2

Mechanisms promoting translocations in editing and switching peripheral B cells.

Wang JH, Gostissa M, Yan CT, Goff P, Hickernell T, Hansen E, Difilippantonio S, Wesemann DR, Zarrin AA, Rajewsky K, Nussenzweig A, Alt FW. Wang JH, et al. Among authors: gostissa m. Nature. 2009 Jul 9;460(7252):231-6. doi: 10.1038/nature08159. Nature. 2009. PMID: 19587764 Free PMC article.

3

Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region.

Gostissa M, Yan CT, Bianco JM, Cogné M, Pinaud E, Alt FW. Gostissa M, et al. Nature. 2009 Dec 10;462(7274):803-7. doi: 10.1038/nature08633. Nature. 2009. PMID: 20010689 Free PMC article.

4

IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances.

Gostissa M, Schwer B, Chang A, Dong J, Meyers RM, Marecki GT, Choi VW, Chiarle R, Zarrin AA, Alt FW. Gostissa M, et al. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2644-9. doi: 10.1073/pnas.1324176111. Epub 2014 Feb 3. Proc Natl Acad Sci U S A. 2014. PMID: 24550291 Free PMC article.

5

Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes.

Hu J, Tepsuporn S, Meyers RM, Gostissa M, Alt FW. Hu J, et al. Among authors: gostissa m. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10269-74. doi: 10.1073/pnas.1410112111. Epub 2014 Jun 30. Proc Natl Acad Sci U S A. 2014. PMID: 24982162 Free PMC article.

6

Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells.

Compagno M, Wang Q, Pighi C, Cheong TC, Meng FL, Poggio T, Yeap LS, Karaca E, Blasco RB, Langellotto F, Ambrogio C, Voena C, Wiestner A, Kasar SN, Brown JR, Sun J, Wu CJ, Gostissa M, Alt FW, Chiarle R. Compagno M, et al. Among authors: gostissa m. Nature. 2017 Feb 23;542(7642):489-493. doi: 10.1038/nature21406. Epub 2017 Feb 15. Nature. 2017. PMID: 28199309 Free PMC article.

7

H2AX prevents DNA breaks from progressing to chromosome breaks and translocations.

Franco S, Gostissa M, Zha S, Lombard DB, Murphy MM, Zarrin AA, Yan C, Tepsuporn S, Morales JC, Adams MM, Lou Z, Bassing CH, Manis JP, Chen J, Carpenter PB, Alt FW. Franco S, et al. Among authors: gostissa m. Mol Cell. 2006 Jan 20;21(2):201-14. doi: 10.1016/j.molcel.2006.01.005. Mol Cell. 2006. PMID: 16427010 Free article.

8

Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching.

Wang JH, Alt FW, Gostissa M, Datta A, Murphy M, Alimzhanov MB, Coakley KM, Rajewsky K, Manis JP, Yan CT. Wang JH, et al. Among authors: gostissa m. J Exp Med. 2008 Dec 22;205(13):3079-90. doi: 10.1084/jem.20082271. Epub 2008 Dec 8. J Exp Med. 2008. PMID: 19064702 Free PMC article.

9

The role of mechanistic factors in promoting chromosomal translocations found in lymphoid and other cancers.

Zhang Y, Gostissa M, Hildebrand DG, Becker MS, Boboila C, Chiarle R, Lewis S, Alt FW. Zhang Y, et al. Among authors: gostissa m. Adv Immunol. 2010;106:93-133. doi: 10.1016/S0065-2776(10)06004-9. Adv Immunol. 2010. PMID: 20728025 Free PMC article. Review.

10

Mechanisms that promote and suppress chromosomal translocations in lymphocytes.

Gostissa M, Alt FW, Chiarle R. Gostissa M, et al. Annu Rev Immunol. 2011;29:319-50. doi: 10.1146/annurev-immunol-031210-101329. Annu Rev Immunol. 2011. PMID: 21219174 Review.

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