Yu Y - Search Results

1

A Designed Metalloenzyme Achieving the Catalytic Rate of a Native Enzyme.

Yu Y, Cui C, Liu X, Petrik ID, Wang J, Lu Y. Yu Y, et al. J Am Chem Soc. 2015 Sep 16;137(36):11570-3. doi: 10.1021/jacs.5b07119. Epub 2015 Sep 8. J Am Chem Soc. 2015. PMID: 26318313 Free PMC article.

2

Transforming a blue copper into a red copper protein: engineering cysteine and homocysteine into the axial position of azurin using site-directed mutagenesis and expressed protein ligation.

Clark KM, Yu Y, Marshall NM, Sieracki NA, Nilges MJ, Blackburn NJ, van der Donk WA, Lu Y. Clark KM, et al. Among authors: yu y. J Am Chem Soc. 2010 Jul 28;132(29):10093-101. doi: 10.1021/ja102632p. J Am Chem Soc. 2010. PMID: 20608676 Free PMC article.

3

Significant increase of oxidase activity through the genetic incorporation of a tyrosine-histidine cross-link in a myoglobin model of heme-copper oxidase.

Liu X, Yu Y, Hu C, Zhang W, Lu Y, Wang J. Liu X, et al. Among authors: yu y. Angew Chem Int Ed Engl. 2012 Apr 27;51(18):4312-6. doi: 10.1002/anie.201108756. Epub 2012 Mar 12. Angew Chem Int Ed Engl. 2012. PMID: 22411709 Free PMC article.

4

Direct EPR observation of a tyrosyl radical in a functional oxidase model in myoglobin during both H2O2 and O2 reactions.

Yu Y, Mukherjee A, Nilges MJ, Hosseinzadeh P, Miner KD, Lu Y. Yu Y, et al. J Am Chem Soc. 2014 Jan 29;136(4):1174-1177. doi: 10.1021/ja4091885. Epub 2014 Jan 14. J Am Chem Soc. 2014. PMID: 24383850 Free PMC article.

5

Metalloprotein design using genetic code expansion.

Hu C, Chan SI, Sawyer EB, Yu Y, Wang J. Hu C, et al. Among authors: yu y. Chem Soc Rev. 2014 Sep 21;43(18):6498-510. doi: 10.1039/c4cs00018h. Chem Soc Rev. 2014. PMID: 24699759 Review.

6

Modulating the Copper-Sulfur Interaction in Type 1 Blue Copper Azurin by Replacing Cys112 with Nonproteinogenic Homocysteine.

Clark KM, Yu Y, van der Donk WA, Blackburn N, Lu Y. Clark KM, et al. Among authors: yu y. Inorg Chem Front. 2014 Feb 1;1(2):153-158. doi: 10.1039/C3QI00096F. Inorg Chem Front. 2014. PMID: 24707355 Free PMC article.

7

Metalloproteins containing cytochrome, iron-sulfur, or copper redox centers.

Liu J, Chakraborty S, Hosseinzadeh P, Yu Y, Tian S, Petrik I, Bhagi A, Lu Y. Liu J, et al. Among authors: yu y. Chem Rev. 2014 Apr 23;114(8):4366-469. doi: 10.1021/cr400479b. Chem Rev. 2014. PMID: 24758379 Free PMC article. Review. No abstract available.

8

Significant enhancement of hPrx1 chaperone activity through lysine acetylation.

Pan Y, Jin JH, Yu Y, Wang J. Pan Y, et al. Among authors: yu y. Chembiochem. 2014 Aug 18;15(12):1773-6. doi: 10.1002/cbic.201402164. Epub 2014 Jul 31. Chembiochem. 2014. PMID: 25082442

9

Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers.

Liu X, Jiang L, Li J, Wang L, Yu Y, Zhou Q, Lv X, Gong W, Lu Y, Wang J. Liu X, et al. Among authors: yu y. J Am Chem Soc. 2014 Sep 24;136(38):13094-7. doi: 10.1021/ja505219r. Epub 2014 Sep 10. J Am Chem Soc. 2014. PMID: 25197956

10

Defining the role of tyrosine and rational tuning of oxidase activity by genetic incorporation of unnatural tyrosine analogs.

Yu Y, Lv X, Li J, Zhou Q, Cui C, Hosseinzadeh P, Mukherjee A, Nilges MJ, Wang J, Lu Y. Yu Y, et al. J Am Chem Soc. 2015 Apr 15;137(14):4594-7. doi: 10.1021/ja5109936. Epub 2015 Apr 1. J Am Chem Soc. 2015. PMID: 25672571 Free PMC article.

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