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The evolutionarily conserved transcription factor PRDM12 controls sensory neuron development and pain perception.
Nagy V, Cole T, Van Campenhout C, Khoung TM, Leung C, Vermeiren S, Novatchkova M, Wenzel D, Cikes D, Polyansky AA, Kozieradzki I, Meixner A, Bellefroid EJ, Neely GG, Penninger JM. Nagy V, et al. Among authors: penninger jm. Cell Cycle. 2015;14(12):1799-808. doi: 10.1080/15384101.2015.1036209. Cell Cycle. 2015. PMID: 25891934 Free PMC article.
Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression.
Andergassen D, Dotter CP, Wenzel D, Sigl V, Bammer PC, Muckenhuber M, Mayer D, Kulinski TM, Theussl HC, Penninger JM, Bock C, Barlow DP, Pauler FM, Hudson QJ. Andergassen D, et al. Among authors: penninger jm. Elife. 2017 Aug 14;6:e25125. doi: 10.7554/eLife.25125. Elife. 2017. PMID: 28806168 Free PMC article.
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders.
Ang CE, Ma Q, Wapinski OL, Fan S, Flynn RA, Lee QY, Coe B, Onoguchi M, Olmos VH, Do BT, Dukes-Rimsky L, Xu J, Tanabe K, Wang L, Elling U, Penninger JM, Zhao Y, Qu K, Eichler EE, Srivastava A, Wernig M, Chang HY. Ang CE, et al. Among authors: penninger jm. Elife. 2019 Jan 10;8:e41770. doi: 10.7554/eLife.41770. Elife. 2019. PMID: 30628890 Free PMC article.
HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases.
Kogler M, Tortola L, Negri GL, Leopoldi A, El-Naggar AM, Mereiter S, Gomez-Diaz C, Nitsch R, Tortora D, Kavirayani AM, Gapp BV, Rao S, Uribesalgo I, Hoffmann D, Cikes D, Novatchkova M, Williams DA, Trent JM, Ikeda F, Daugaard M, Hagelkruys A, Sorensen PH, Penninger JM. Kogler M, et al. Among authors: penninger jm. Cancer Res. 2020 Jul 15;80(14):3009-3022. doi: 10.1158/0008-5472.CAN-19-2270. Epub 2020 May 4. Cancer Res. 2020. PMID: 32366477 Free PMC article.
Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability.
Olie CS, van der Wal E, Cikes D, Maton L, de Greef JC, Lin IH, Chen YF, Kareem E, Penninger JM, Kessler BM, Raz V. Olie CS, et al. Among authors: penninger jm. Sci Rep. 2020 Oct 19;10(1):17621. doi: 10.1038/s41598-020-74676-8. Sci Rep. 2020. PMID: 33077830 Free PMC article.
ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology.
Gawish R, Starkl P, Pimenov L, Hladik A, Lakovits K, Oberndorfer F, Cronin SJ, Ohradanova-Repic A, Wirnsberger G, Agerer B, Endler L, Capraz T, Perthold JW, Cikes D, Koglgruber R, Hagelkruys A, Montserrat N, Mirazimi A, Boon L, Stockinger H, Bergthaler A, Oostenbrink C, Penninger JM, Knapp S. Gawish R, et al. Among authors: penninger jm. Elife. 2022 Jan 13;11:e74623. doi: 10.7554/eLife.74623. Elife. 2022. PMID: 35023830 Free PMC article.
The HUSH complex controls brain architecture and protocadherin fidelity.
Hagelkruys A, Horrer M, Taubenschmid-Stowers J, Kavirayani A, Novatchkova M, Orthofer M, Pai TP, Cikes D, Zhuk S, Balmaña M, Esk C, Koglgruber R, Moeseneder P, Lazovic J, Zopf LM, Cronin SJF, Elling U, Knoblich JA, Penninger JM. Hagelkruys A, et al. Among authors: penninger jm. Sci Adv. 2022 Nov 4;8(44):eabo7247. doi: 10.1126/sciadv.abo7247. Epub 2022 Nov 4. Sci Adv. 2022. PMID: 36332029 Free PMC article.
638 results