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Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds.
Delfosse V, Dendele B, Huet T, Grimaldi M, Boulahtouf A, Gerbal-Chaloin S, Beucher B, Roecklin D, Muller C, Rahmani R, Cavaillès V, Daujat-Chavanieu M, Vivat V, Pascussi JM, Balaguer P, Bourguet W. Delfosse V, et al. Among authors: balaguer p. Nat Commun. 2015 Sep 3;6:8089. doi: 10.1038/ncomms9089. Nat Commun. 2015. PMID: 26333997 Free PMC article.
Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor.
Duret C, Daujat-Chavanieu M, Pascussi JM, Pichard-Garcia L, Balaguer P, Fabre JM, Vilarem MJ, Maurel P, Gerbal-Chaloin S. Duret C, et al. Among authors: balaguer p. Mol Pharmacol. 2006 Jul;70(1):329-39. doi: 10.1124/mol.105.022046. Epub 2006 Apr 11. Mol Pharmacol. 2006. PMID: 16608920
Negative regulation of hormone signaling by RIP140.
Augereau P, Badia E, Balaguer P, Carascossa S, Castet A, Jalaguier S, Cavaillès V. Augereau P, et al. Among authors: balaguer p. J Steroid Biochem Mol Biol. 2006 Dec;102(1-5):51-9. doi: 10.1016/j.jsbmb.2006.09.005. Epub 2006 Oct 23. J Steroid Biochem Mol Biol. 2006. PMID: 17056252 Review.
198 results