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Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility.
Hill JW, Elias CF, Fukuda M, Williams KW, Berglund ED, Holland WL, Cho YR, Chuang JC, Xu Y, Choi M, Lauzon D, Lee CE, Coppari R, Richardson JA, Zigman JM, Chua S, Scherer PE, Lowell BB, Brüning JC, Elmquist JK. Hill JW, et al. Among authors: xu y. Cell Metab. 2010 Apr 7;11(4):286-97. doi: 10.1016/j.cmet.2010.03.002. Cell Metab. 2010. PMID: 20374961 Free PMC article.
Estrogens stimulate serotonin neurons to inhibit binge-like eating in mice.
Cao X, Xu P, Oyola MG, Xia Y, Yan X, Saito K, Zou F, Wang C, Yang Y, Hinton A Jr, Yan C, Ding H, Zhu L, Yu L, Yang B, Feng Y, Clegg DJ, Khan S, DiMarchi R, Mani SK, Tong Q, Xu Y. Cao X, et al. Among authors: xu p, xu y. J Clin Invest. 2014 Oct;124(10):4351-62. doi: 10.1172/JCI74726. Epub 2014 Aug 26. J Clin Invest. 2014. PMID: 25157819 Free PMC article.
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