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Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling.
Richter M, Murtaza N, Scharrenberg R, White SH, Johanns O, Walker S, Yuen RKC, Schwanke B, Bedürftig B, Henis M, Scharf S, Kraus V, Dörk R, Hellmann J, Lindenmaier Z, Ellegood J, Hartung H, Kwan V, Sedlacik J, Fiehler J, Schweizer M, Lerch JP, Hanganu-Opatz IL, Morellini F, Scherer SW, Singh KK, Calderon de Anda F. Richter M, et al. Among authors: sedlacik j. Mol Psychiatry. 2019 Sep;24(9):1329-1350. doi: 10.1038/s41380-018-0025-5. Epub 2018 Feb 21. Mol Psychiatry. 2019. PMID: 29467497 Free PMC article.
TAOK2 rescues autism-linked developmental deficits in a 16p11.2 microdeletion mouse model.
Scharrenberg R, Richter M, Johanns O, Meka DP, Rücker T, Murtaza N, Lindenmaier Z, Ellegood J, Naumann A, Zhao B, Schwanke B, Sedlacik J, Fiehler J, Hanganu-Opatz IL, Lerch JP, Singh KK, de Anda FC. Scharrenberg R, et al. Among authors: sedlacik j. Mol Psychiatry. 2022 Nov;27(11):4707-4721. doi: 10.1038/s41380-022-01785-3. Epub 2022 Sep 19. Mol Psychiatry. 2022. PMID: 36123424 Free PMC article.
101 results