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Early Initiation Rather Than Prolonged Duration of Antiretroviral Therapy in HIV Infection Contributes to the Normalization of CD8 T-Cell Counts.
Cao W, Mehraj V, Trottier B, Baril JG, Leblanc R, Lebouche B, Cox J, Tremblay C, Lu W, Singer J, Li T, Routy JP; Montreal Primary HIV Infection Study Group; Vézina S, Charest L, Milne M, Huchet E, Lavoie S, Friedman J, Duchastel M, Villielm F, Côté P, Potter M, Lessard B, Charron MA, Dufresne S, Turgeon ME, Rouleau D, Labrecque L, Fortin C, de Pokomandy A, Hal-Gagné V, Munoz M, Deligne B, Martel-Laferrière V, Gilmore N, Fletcher M, Szabo J. Cao W, et al. Among authors: vezina s. Clin Infect Dis. 2016 Jan 15;62(2):250-257. doi: 10.1093/cid/civ809. Epub 2015 Sep 8. Clin Infect Dis. 2016. PMID: 26349551 Free PMC article.
Changes in function of HIV-specific T-cell responses with increasing time from infection.
Ndongala ML, Kamya P, Boulet S, Peretz Y, Rouleau D, Tremblay C, Leblanc R, Côté P, Baril JG, Thomas R, Vézina S, Boulassel MR, Routy JP, Sékaly RP, Bernard NF. Ndongala ML, et al. Among authors: vezina s. Viral Immunol. 2010 Apr;23(2):159-68. doi: 10.1089/vim.2009.0084. Viral Immunol. 2010. PMID: 20373996 Free PMC article.
Receptor-ligand requirements for increased NK cell polyfunctional potential in slow progressors infected with HIV-1 coexpressing KIR3DL1*h/*y and HLA-B*57.
Kamya P, Boulet S, Tsoukas CM, Routy JP, Thomas R, Côté P, Boulassel MR, Baril JG, Kovacs C, Migueles SA, Connors M, Suscovich TJ, Brander C, Tremblay CL, Bernard N; Canadian Cohort of HIV Infected Slow Progressors. Kamya P, et al. J Virol. 2011 Jun;85(12):5949-60. doi: 10.1128/JVI.02652-10. Epub 2011 Apr 6. J Virol. 2011. PMID: 21471235 Free PMC article.
Tolerability is more important than simplicity for treatment durability.
Trottier B, Machouf N, Huchet E, Lavoie S, Vezina S, Boissonnault M, Charest L, Munoz M, Legault D, Longpré D, Thomas R. Trottier B, et al. Among authors: vezina s. J Int AIDS Soc. 2014 Nov 2;17(4 Suppl 3):19765. doi: 10.7448/IAS.17.4.19765. eCollection 2014. J Int AIDS Soc. 2014. PMID: 25397509 Free PMC article.
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