Marciniak SJ - Search Results

1

Interactions between N-linked glycosylation and polymerisation of neuroserpin within the endoplasmic reticulum.

Moriconi C, Ordoñez A, Lupo G, Gooptu B, Irving JA, Noto R, Martorana V, Manno M, Timpano V, Guadagno NA, Dalton L, Marciniak SJ, Lomas DA, Miranda E. Moriconi C, et al. Among authors: marciniak sj. FEBS J. 2015 Dec;282(23):4565-79. doi: 10.1111/febs.13517. Epub 2015 Oct 3. FEBS J. 2015. PMID: 26367528 Free PMC article.

2

Unravelling the twists and turns of the serpinopathies.

Roussel BD, Irving JA, Ekeowa UI, Belorgey D, Haq I, Ordóñez A, Kruppa AJ, Duvoix A, Rashid ST, Crowther DC, Marciniak SJ, Lomas DA. Roussel BD, et al. Among authors: marciniak sj. FEBS J. 2011 Oct;278(20):3859-67. doi: 10.1111/j.1742-4658.2011.08201.x. Epub 2011 Jun 20. FEBS J. 2011. PMID: 21624056 Free article. Review.

3

Endoplasmic reticulum dysfunction in neurological disease.

Roussel BD, Kruppa AJ, Miranda E, Crowther DC, Lomas DA, Marciniak SJ. Roussel BD, et al. Among authors: marciniak sj. Lancet Neurol. 2013 Jan;12(1):105-18. doi: 10.1016/S1474-4422(12)70238-7. Lancet Neurol. 2013. PMID: 23237905 Free article. Review.

4

Characterising the association of latency with α(1)-antitrypsin polymerisation using a novel monoclonal antibody.

Tan L, Perez J, Mela M, Miranda E, Burling KA, Rouhani FN, DeMeo DL, Haq I, Irving JA, Ordóñez A, Dickens JA, Brantly M, Marciniak SJ, Alexander GJ, Gooptu B, Lomas DA. Tan L, et al. Among authors: marciniak sj. Int J Biochem Cell Biol. 2015 Jan;58:81-91. doi: 10.1016/j.biocel.2014.11.005. Epub 2014 Nov 13. Int J Biochem Cell Biol. 2015. PMID: 25462157 Free PMC article.

5

Neuroserpin polymers activate NF-kappaB by a calcium signaling pathway that is independent of the unfolded protein response.

Davies MJ, Miranda E, Roussel BD, Kaufman RJ, Marciniak SJ, Lomas DA. Davies MJ, et al. Among authors: marciniak sj. J Biol Chem. 2009 Jul 3;284(27):18202-9. doi: 10.1074/jbc.M109.010744. Epub 2009 May 7. J Biol Chem. 2009. PMID: 19423713 Free PMC article.

6

Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins.

Kroeger H, Miranda E, MacLeod I, Pérez J, Crowther DC, Marciniak SJ, Lomas DA. Kroeger H, et al. Among authors: marciniak sj. J Biol Chem. 2009 Aug 21;284(34):22793-802. doi: 10.1074/jbc.M109.027102. Epub 2009 Jun 23. J Biol Chem. 2009. PMID: 19549782 Free PMC article.

7

The serpinopathies studying serpin polymerization in vivo.

Irving JA, Ekeowa UI, Belorgey D, Haq I, Gooptu B, Miranda E, Pérez J, Roussel BD, Ordóñez A, Dalton LE, Thomas SE, Marciniak SJ, Parfrey H, Chilvers ER, Teckman JH, Alam S, Mahadeva R, Rashid ST, Vallier L, Lomas DA. Irving JA, et al. Among authors: marciniak sj. Methods Enzymol. 2011;501:421-66. doi: 10.1016/B978-0-12-385950-1.00018-3. Methods Enzymol. 2011. PMID: 22078544

8

Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in alpha1-antitrypsin deficiency.

Ordóñez A, Snapp EL, Tan L, Miranda E, Marciniak SJ, Lomas DA. Ordóñez A, et al. Among authors: marciniak sj. Hepatology. 2013 May;57(5):2049-60. doi: 10.1002/hep.26173. Epub 2013 Mar 14. Hepatology. 2013. PMID: 23197448 Free PMC article.

9

A single-chain variable fragment intrabody prevents intracellular polymerization of Z α1-antitrypsin while allowing its antiproteinase activity.

Ordóñez A, Pérez J, Tan L, Dickens JA, Motamedi-Shad N, Irving JA, Haq I, Ekeowa U, Marciniak SJ, Miranda E, Lomas DA. Ordóñez A, et al. Among authors: marciniak sj. FASEB J. 2015 Jun;29(6):2667-78. doi: 10.1096/fj.14-267351. Epub 2015 Mar 10. FASEB J. 2015. PMID: 25757566 Free PMC article.

10

Intracellular serpins, firewalls and tissue necrosis.

Marciniak SJ, Lomas DA. Marciniak SJ, et al. Trends Cell Biol. 2008 Feb;18(2):45-7. doi: 10.1016/j.tcb.2007.11.006. Epub 2008 Jan 22. Trends Cell Biol. 2008. PMID: 18215520

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