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BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis.
Canver MC, Smith EC, Sher F, Pinello L, Sanjana NE, Shalem O, Chen DD, Schupp PG, Vinjamur DS, Garcia SP, Luc S, Kurita R, Nakamura Y, Fujiwara Y, Maeda T, Yuan GC, Zhang F, Orkin SH, Bauer DE. Canver MC, et al. Among authors: pinello l. Nature. 2015 Nov 12;527(7577):192-7. doi: 10.1038/nature15521. Epub 2015 Sep 16. Nature. 2015. PMID: 26375006 Free PMC article.
Statistical inference with a manifold-constrained RNA velocity model uncovers cell cycle speed modulations.
Lederer AR, Leonardi M, Talamanca L, Herrera A, Droin C, Khven I, Carvalho HJF, Valente A, Mantes AD, Arabí PM, Pinello L, Naef F, Manno G. Lederer AR, et al. Among authors: pinello l. bioRxiv [Preprint]. 2024 Jan 22:2024.01.18.576093. doi: 10.1101/2024.01.18.576093. bioRxiv. 2024. Update in: Nat Methods. 2024 Oct 31. doi: 10.1038/s41592-024-02471-8. PMID: 38328127 Free PMC article. Updated. Preprint.
A motif-independent metric for DNA sequence specificity.
Pinello L, Lo Bosco G, Hanlon B, Yuan GC. Pinello L, et al. BMC Bioinformatics. 2011 Oct 21;12:408. doi: 10.1186/1471-2105-12-408. BMC Bioinformatics. 2011. PMID: 22017798 Free PMC article.
An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.
Bauer DE, Kamran SC, Lessard S, Xu J, Fujiwara Y, Lin C, Shao Z, Canver MC, Smith EC, Pinello L, Sabo PJ, Vierstra J, Voit RA, Yuan GC, Porteus MH, Stamatoyannopoulos JA, Lettre G, Orkin SH. Bauer DE, et al. Among authors: pinello l. Science. 2013 Oct 11;342(6155):253-7. doi: 10.1126/science.1242088. Science. 2013. PMID: 24115442 Free PMC article.
Applications of alignment-free methods in epigenomics.
Pinello L, Lo Bosco G, Yuan GC. Pinello L, et al. Brief Bioinform. 2014 May;15(3):419-30. doi: 10.1093/bib/bbt078. Epub 2013 Nov 6. Brief Bioinform. 2014. PMID: 24197932 Free PMC article. Review.
Distinct and combinatorial functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in mouse embryonic stem cell identity.
Das PP, Shao Z, Beyaz S, Apostolou E, Pinello L, De Los Angeles A, O'Brien K, Atsma JM, Fujiwara Y, Nguyen M, Ljuboja D, Guo G, Woo A, Yuan GC, Onder T, Daley G, Hochedlinger K, Kim J, Orkin SH. Das PP, et al. Among authors: pinello l. Mol Cell. 2014 Jan 9;53(1):32-48. doi: 10.1016/j.molcel.2013.11.011. Epub 2013 Dec 19. Mol Cell. 2014. PMID: 24361252 Free PMC article.
126 results